ArticleBMC research notes2011
Acidochromogenicity is a common characteristic in nontuberculous mycobacteria.
Article in BMC research notes, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 8 citations in OpenAlex.
- Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3.Tuberculosis (Edinburgh, Scotland) · 2023Article
- Brought to you courtesy of the red, white, and blue-pigments of nontuberculous mycobacteria.AIMS microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn acidic environment is something likely encountered by mycobacteria in the environment or in a human host. Previously mycobacterial species had been known to produce carotenoid pigments in response to light or constitutively.
resultsWe have tested the ability of various mycobacteria to grow on solid agar plates of differing acidity, and have shown that many species of mycobacteria previously thought to not produce pigment are pigmented when exposed to acidic stress. The Mycobacterium smegmatis promoter region upstream of the genes homologous to those of other mycobacterial species known to code for proteins involved in carotenoid biosynthesis was found to be upregulated under acidic stress.
conclusionsMycobacterial species can produce pigment in response to conditions not previously known to induce chromogenicity in mycobacteria. In addition many mycobacterial species previously thought to not produce pigment are actually chromogenic under acidic conditions.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.