Evidence map›Paper›PMID 22032859›Full record

ArticleBMC research notes2011

gViz, a novel tool for the visualization of co-expression networks.

Raphaël Helaers, Eric Bareke, Bertrand De Meulder, Michael Pierre, Sophie Depiereux, Naji Habra, Eric Depiereux

Abstract read
In one paragraph

Article in BMC research notes, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. N-terminus ofeLife · 2024
    Article
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  4. BAP1 Loss Is Associated with DNA Methylomic Repatterning in Highly Aggressive Class 2 Uveal Melanomas.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raphaël HelaersBioinformatics and Biostatistics unit, Molecular Biology Research Unit (MBRU), Namur Center for Complex Systems (NAXYS), University of Namur (FUNDP), 61 Rue de Bruxelles, B-5000 Namur, Belgium. eric.bareke@fundp.ac.be.
Eric Bareke
Bertrand De Meulder
Michael Pierre
Sophie Depiereux
Naji Habra
Eric Depiereux

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe quantity of microarray data available on the Internet has grown dramatically over the past years and now represents millions of Euros worth of underused information. One way to use this data is through co-expression analysis. To avoid a certain amount of bias, such data must often be analyzed at the genome scale, for example by network representation. The identification of co-expression networks is an important means to unravel gene to gene interactions and the underlying functional relationship between them. However, it is very difficult to explore and analyze a network of such dimensions. Several programs (Cytoscape, yEd) have already been developed for network analysis; however, to our knowledge, there are no available GraphML compatible programs.

findingsWe designed and developed gViz, a GraphML network visualization and exploration tool. gViz is built on clustering coefficient-based algorithms and is a novel tool to visualize and manipulate networks of co-expression interactions among a selection of probesets (each representing a single gene or transcript), based on a set of microarray co-expression data stored as an adjacency matrix.

conclusionsWe present here gViz, a software tool designed to visualize and explore large GraphML networks, combining network theory, biological annotation data, microarray data analysis and advanced graphical features.

Identifiers

PMID22032859
PMCPMC3214194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.