ArticleBehavioral and brain functions : BBF2011
Autonomic nervous alterations associated with daily level of fatigue.
Article in Behavioral and brain functions : BBF, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 89 citations in OpenAlex.
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- Distinct functional connectivity patterns in myalgic encephalomyelitis and long COVID patients during cognitive fatigue: a 7 Tesla task-fMRI study.Journal of translational medicine · 2026Article
- A Deep Learning Approach for Mental Fatigue State Assessment.Sensors (Basel, Switzerland) · 2025Article
- Estimating psychophysiological loads by repeated temperature steps on humans using a state-space model.PloS one · 2025Article
- Individually optimized estimation of energy expenditure in rescue workers using a tri-axial accelerometer and heart rate monitor.Frontiers in physiology · 2024Article
- Acute Effects of Fatigue on Cardiac Autonomic Nervous Activity.Journal of sports science & medicine · 2023Article
- Dysautonomia and small fiber neuropathy in post-COVID condition and Chronic Fatigue Syndrome.Journal of translational medicine · 2023Article
- Autonomic function measurements for evaluating fatigue and quality of life in patients with breast cancer undergoing radiation therapy: a prospective longitudinal study.Radiation oncology (London, England) · 2023Article
- Clinical studies on the electric automatic massage therapy for recovery of acute sports fatigue.Technology and health care : official journal of the European Society for Engineering and Medicine · 2023Article
- Clinical efficacy of vibration stimulation therapy to relieve acute exercise fatigue.Technology and health care : official journal of the European Society for Engineering and Medicine · 2023Article
- Brain fog of post-COVID-19 condition and Chronic Fatigue Syndrome, same medical disorder?Journal of translational medicine · 2022Article
- Neural effects of viewing children's faces on mental fatigue: a magnetoencephalography study.Experimental brain research · 2022Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFatigue is a common symptom in both sick and healthy people. We examined autonomic nervous alterations associated with fatigue to clarify the mechanisms underlying fatigue.
methodsThe study group consisted of 19 healthy participants who performed a 2-back test for 30 min as a fatigue-inducing mental task session. Before and after the session, they completed the advanced trail making test (ATMT) for 30 min for mental fatigue evaluation, subjective scales to measure fatigue sensation, and underwent electrocardiography to allow assessment of autonomic nerve activities.
resultsAfter the fatigue-inducing task, the total error counts on the ATMT tended to increase (P = 0.076); the ATMT for total trial counts (P = 0.001), the subjective level of fatigue (P < 0.001), and the % low-frequency power (%LF) (P = 0.035) increased significantly; and the % high-frequency power (%HF) decreased compared with before the fatigue-inducing task although this did not reach the statistical significance (P = 0.170). Although LF measured in absolute units did not change significantly before and after the fatigue-inducing task (P = 0.771), and HF measured in absolute units decreased after the task (P = 0.020). The %LF and LF/HF ratio were positively associated with the daily level of fatigue evaluated using Chalder's fatigue scale. In addition, %HF was negatively associated with the fatigue score.
conclusionsIncreased sympathetic activity and decreased parasympathetic activity may be characteristic features of both acute and daily levels of fatigue. Our findings provide new perspectives on the mechanisms underlying fatigue.
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