ArticleJournal of the Royal Society, Interface2012
Damped and persistent oscillations in a simple model of cell crawling.
Article in Journal of the Royal Society, Interface, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- A continuum mechanical model of cell motion driven by a biphasic traction stress.Journal of the Royal Society, Interface · 2024Article
- Role of intracellular poroelasticity on freezing-induced deformation of cells in engineered tissues.Journal of the Royal Society, Interface · 2016Article
- A hybrid mathematical model for self-organizing cell migration in the zebrafish lateral line.Journal of mathematical biology · 2015Article
- Effects of adhesion dynamics and substrate compliance on the shape and motility of crawling cells.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A very simple, one-dimensional, discrete, autonomous model of cell crawling is proposed; the model involves only three or four coupled first-order differential equations. This form is sufficient to describe many general features of cell migration, including both steady forward motion and oscillatory progress. Closed-form expressions for crawling speeds and internal forces are obtained in terms of dimensionless parameters that characterize active intracellular processes and the passive mechanical properties of the cell. Two versions of the model are described: a basic cell model with simple elastic coupling between front and rear, which exhibits stable, steady forward crawling after initial transient oscillations have decayed, and a poroelastic model, which can exhibit oscillatory crawling in the steady state.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.