Evidence map›Paper›PMID 22031527›Full record

ArticleThe Journal of general virology2012

Characterization of novel canine bocaviruses and their association with respiratory disease.

Amit Kapoor, Natasha Mehta, Edward J Dubovi, Peter Simmonds, Lakshmanan Govindasamy, Jan L Medina, Craig Street, Shelly Shields, W Ian Lipkin

Open access · greenAbstract read
In one paragraph

Article in The Journal of general virology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Predominance of Canine Parainfluenza Virus andPathogens (Basel, Switzerland) · 2023
    Article
  7. Old and Novel Enteric Parvoviruses of Dogs.Pathogens (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Virome of crab-eating (Cerdocyon thous) and pampas foxes (Lycalopex gymnocercus) from southern Brazil and Uruguay.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Amit KapoorCenter for Infection and Immunity, Columbia University, New York 10032, USA.
Natasha MehtaCenter for Infection and Immunity, Columbia University, New York 10032, USA.
Edward J DuboviCollege of Veterinary Medicine at Cornell, Ithaca, NY 14853, USA.
Peter SimmondsCentre for Immunology, Infection and Evolution, University of Edinburgh, Edinburgh EH9 3JT, UK.
Lakshmanan GovindasamyDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32610, USA.
Jan L MedinaCenter for Infection and Immunity, Columbia University, New York 10032, USA.
Craig StreetCenter for Infection and Immunity, Columbia University, New York 10032, USA.
Shelly ShieldsPfizer Veterinary Medicine Research and Development, New York 10017, USA.
W Ian LipkinCenter for Infection and Immunity, Columbia University, New York 10032, USA.
Columbia University · USCornell University · USPfizer (United States) · USUniversity of Edinburgh · GBUniversity of Florida · US

Funding

Viral Pathogenesis and TherapeuticsU54AI057158 · NIAID · WADSWORTH CENTER · PI LIPKIN, W. IAN · 2003 to 2014
$100.8M
Development of Complement Modulating Therapeutics for AMDR24EY017404 · NEI · UNIVERSITY OF UTAH · PI HAGEMAN, GREGORY S · 2006 to 2010
$14.8M
Identification and characterization of cellular factors involved in HCV entryR01AI072613 · NIAID · ROCKEFELLER UNIVERSITY · PI RICE, CHARLES M · 2007 to 2016
$4.7M
Viral Arrays for BiodefenseU01AI070411 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2006 to 2010
$4.4M
Risk of Viral Emergence from BatsR01AI079231 · NIAID · ECOHEALTH ALLIANCE, INC. · PI DASZAK, PETER · 2008 to 2012
$2.6M
Simianizing hepatitis C: Defining the species-tropism of a hepatotropic virusR01AI090055 · NIAID · ROCKEFELLER UNIVERSITY · PI RICE, CHARLES M · 2010 to 2014
$2.1M
Molecular Characterization of Novel AstrovirusesR21AI090196 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KAPOOR, AMIT · 2010 to 2011
$454k
Study of a novel picornavirus genus associated with Acute Flaccid ParalysisR21AI081132 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KAPOOR, AMIT · 2011 to 2012
$448k
NEI NIH HHS EY017404NEI NIH HHS R24 EY017404NIAID NIH HHS AI070411NIAID NIH HHS AI072613NIAID NIH HHS AI079231NIAID NIH HHS AI081132NIAID NIH HHS AI090055NIAID NIH HHS AI090196NIAID NIH HHS AI57158NIAID NIH HHS R01 AI072613NIAID NIH HHS R01 AI079231NIAID NIH HHS R01 AI090055NIAID NIH HHS R21 AI081132NIAID NIH HHS R21 AI090196NIAID NIH HHS U01 AI070411NIAID NIH HHS U54 AI057158Wellcome Trust 095831
6 · The paper itself

Abstract

We report the first identification, genetic characterization and disease association studies of several novel species of canine bocaviruses (CBoV). Evolutionary analysis confirmed that CBoV are genetically distinct from the only other known canine bocavirus, minute virus of canines, with which they share less than 63, 62 and 64 % protein identity in NS, NP and VP genes, respectively. Comparative genetic analysis of 37 VP gene variants found in diseased and healthy animals showed that these novel viruses are genetically highly diverse and are common in canine respiratory infections that have remained undetected until now. Interestingly, we observed that a CBoV genotype with a unique deletion in the VP2 gene was significantly more prevalent in animals with respiratory diseases compared with healthy animals.

Indexed as

AnimalsBocavirusCluster AnalysisDNA, ViralDog DiseasesDogsModels, MolecularMolecular ConformationMolecular Sequence DataParvoviridae InfectionsPhylogenySequence Analysis, DNASequence Homology, Amino AcidViral ProteinsDNA, ViralViral Proteins

Identifiers

PMID22031527
PMCPMC3352345
OpenAlexW2095517320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.