ArticleJournal of perinatology : official journal of the California Perinatal Association2012
Safety of chlorhexidine gluconate used for skin antisepsis in the preterm infant.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 116 citations in OpenAlex.
- Umbilical cord cleansing with chlorhexidine in neonates: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2016Pooled it
- Comparative efficacy of topical povidone-iodine and chlorhexidine gel on dental plaque regrowth in toddlers: A randomized controlled trial.Clinical and experimental dental research · 2023Trial
- One size does not fit all: why universal decolonization strategies to prevent methicillin-resistant Staphylococcus aureus colonization and infection in adult intensive care units may be inappropriate for neonatal intensive care units.Journal of perinatology : official journal of the California Perinatal Association · 2014Trial
- Comment on 'Dermatological Safety of Chlorhexidine-Impregnated Dressings in Paediatric Intensive Care: A Randomised Clinical Trial'.Nursing in critical care · 2026Article
- Seeing beyond the obvious: pragmatic skin care guidance for infants 22-24 weeks gestational age.Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- The use of 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to central venous catheterization in infants: a national survey of the Italian Society of Neonatology.Italian journal of pediatrics · 2025Article
- Impact of chlorhexidine and emollient cleansing on bloodstream infections in a Neonatal ICU.Southern African journal of infectious diseases · 2025Article
- Effectiveness and safety of chlorhexidine gluconate double-cleansing for surgical site infection prevention in neonatal intensive care unit surgical patients.Annals of surgical treatment and research · 2024Article
- Safety and efficacy of whole-body chlorhexidine gluconate cleansing with or without emollient in hospitalised neonates (NeoCHG): a multicentre, randomised, open-label, factorial pilot trial.EClinicalMedicine · 2024Article
- New Insights into Cutaneous Asepsis: Synergism between Pfaffia and Rosemary Extracts.Antibiotics (Basel, Switzerland) · 2024Article
- Microbiome dysbiosis: a modifiable state and target to prevent Staphylococcus aureus infections and other diseases in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2024Review
- Antiseptic solutions for skin preparation during central catheter insertion in neonates.The Cochrane database of systematic reviews · 2023Review
- Strategies to prevent surgical site infections in acute-care hospitals: 2022 Update.Infection control and hospital epidemiology · 2023Article
- Myelin toxicity of chlorhexidine in zebrafish larvae.Pediatric research · 2023Article
- Assessment of Alcohol Exposure From Alcohol-Based Disinfectants Among Premature Infants in Neonatal Incubators in Japan.JAMA network open · 2023Article
- Chlorhexidine bathing in a tertiary care neonatal intensive care unit: A pilot study.PloS one · 2023Article
- Efficacy of plasma activated saline in a co-culture infection control model.Scientific reports · 2022Article
- Neonatal sepsis and the skin microbiome.Journal of perinatology : official journal of the California Perinatal Association · 2022Review
- In-vitro determination of antimicrobial activities of Eruca sativa seed oil against antibiotic-resistant gram-negative clinical isolates from neonates: a future prospect.BMC complementary medicine and therapies · 2022Article
- Prevention of Surgical Site Infections in Neonates and Children: Non-Pharmacological Measures of Prevention.Antibiotics (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Chlorhexidine gluconate (CHG) is a widely used topical antiseptic that is recommended by the Centers for Disease Control and Prevention for skin cleansing before central venous catheter insertion in adults and children. Because of limited safety data, CHG is not recommended for use in children <2 months of age. CHG is, however, frequently used in Neonatal Intensive Care Units across the United States. Here, we will review the safety of CHG use in preterm infants.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.