Evidence map›Paper›PMID 22030237›Full record

ReviewTrends in immunology2012

Participation of blood vessel cells in human adaptive immune responses.

Jordan S Pober, George Tellides

Abstract readReview
In one paragraph

Review in Trends in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Roles of endothelial cells during infection.Current opinion in immunology · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. The crossroad between tumor and endothelial cells.Clinical and experimental medicine · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Nanoparticle-Based Interventions for Liver Transplantation.International journal of molecular sciences · 2023
    Review
  16. Article
  17. Cholinergic regulation of vascular endothelial function by human ChATProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Article
  20. Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jordan S PoberYale University School of Medicine, PO Box 208089, 10 Amistad Street, RM 401, New Haven, CT 06520-8089, USA. jordan.pober@yale.edu
George Tellides

Funding

SOCS-1 and endothelial dysfunction in graft arteriosclerosisP01HL070295 · NHLBI · YALE UNIVERSITY · PI POBER, JORDAN S · 2001 to 2010
$17.9M
Presentation of Alloantigen by Human Vascular CellsR01HL051014 · NHLBI · YALE UNIVERSITY · PI MANES, THOMAS DAVID, POBER, JORDAN S · 1994 to 2019
$10.4M
PROTEINS OF THE ENDOTHELIAL CELL SURFACER01HL036003 · NHLBI · YALE UNIVERSITY · PI KLUGER, MARTIN S, POBER, JORDAN S · 1985 to 2015
$5.7M
PROTEINS OF THE ENDOTHELIAL CELL SURFACER37HL036003 · NHLBI · YALE UNIVERSITY · PI POBER, JORDAN S · 1992 to 2001
$664k
NHLBI NIH HHS HL-036003NHLBI NIH HHS HL-051014NHLBI NIH HHS HL-070295NHLBI NIH HHS P01 HL070295NHLBI NIH HHS R01 HL036003NHLBI NIH HHS R01 HL051014NHLBI NIH HHS R37 HL036003
6 · The paper itself

Abstract

Circulating T cells contact blood vessels either when they extravasate across the walls of microvessels into inflamed tissues or when they enter into the walls of larger vessels in inflammatory diseases such as atherosclerosis. The blood vessel wall is largely composed of three cell types: endothelial cells lining the entire vascular tree; pericytes supporting the endothelium of microvessels; and smooth muscle cells forming the bulk of large vessel walls. Each of these cell types interacts with and alters the behavior of infiltrating T cells in different ways, making these cells active participants in the processes of immune-mediated inflammation. In this review, we compare and contrast what is known about the nature of these interactions in humans.

Indexed as

Adaptive ImmunityAnimalsBlood VesselsCell MovementEndothelial CellsHumansT-Lymphocytes

Identifiers

PMID22030237
PMCPMC3253953

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.