Evidence map›Paper›PMID 22030136›Full record

ArticleJournal of affective disorders2012

Under-treatment of depression in older persons.

Lisa C Barry, Janet J Abou, Arthur A Simen, Thomas M Gill

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 118 citations in OpenAlex.

  1. Pooled it
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  17. Major depressive disorder.Nature reviews. Disease primers · 2023
    Review
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lisa C BarryUConn Center on Aging, University of Connecticut Health Center, Farmington, CT 06030-5215, United States. LiBarry@uchc.edu
Janet J Abou
Arthur A Simen
Thomas M Gill
Yale University · USLos Angeles Medical Center · USUConn Health · US

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Yale Training Program in Geriatric Clinical Epidemiology and Aging-Related ResearchT32AG019134 · NIA · YALE UNIVERSITY · PI Terri R. Fried · 2001 to 2026
$7.5M
Epidemiology of Disability and Recovery in Older PersonsR37AG017560 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2005 to 2014
$7.3M
VULNERABILITY, INTERVENING EVENTS &DISABILITY IN AGINGR01AG017560 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2000 to 2025
$7.0M
Epidemiology of Bathing Disability in Elderly PersonsR01AG022993 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2004 to 2007
$1.6M
Research Training in Disability &Disabling DisordersK24AG021507 · NIA · YALE UNIVERSITY · PI GILL, THOMAS MICHAEL · 2003 to 2012
$1.6M
Depression and Disability in Older Persons: Untangling ComplexitiesK01AG031324 · NIA · YALE UNIVERSITY · PI BARRY, LISA C · 2008 to 2012
$618k
GENETICS OF REPRODUCTIVE LONGEVITY IN DROSOPHILAR01AG001934 · NIA · UNIVERSITY OF TEXAS AUSTIN · PI HIRAIZUMI, YUICHIRO · 1985 to 1987
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NIA NIH HHS K01 AG031324NIA NIH HHS K01AG031324NIA NIH HHS K24 AG021507NIA NIH HHS K24AG021507NIA NIH HHS P30 AG021342NIA NIH HHS P30AG21342NIA NIH HHS R01 AG017560NIA NIH HHS R01AG022993NIA NIH HHS R37 AG017560NIA NIH HHS R37AG17560NIA NIH HHS T32 AG019134NIA NIH HHS T32AG1934
6 · The paper itself

Abstract

backgroundDue to the cross-sectional design of most existing studies, longitudinal characterization of treatment for depression in older persons is largely unknown.

methodSeven hundred fifty-four men and women (aged 70+ years) underwent monthly assessments of mental health professional use and 18-month assessments of antidepressant medication use and depressive symptoms over 9 years. Scores of ≥20 on the Center for Epidemiological Studies-Depression (CES-D) scale denoted depression. We evaluated trends in depression treatment over time in the entire sample and among the depressed participants. Using generalized linear models, we determined characteristics associated with receiving treatment for depression in these groups and among those with persistent depression.

resultsDuring the 9-year follow-up period (1998-2007), 339 (45.0%) of the participants reported depression treatment. Over time, antidepressant use alone decreased (p trend<0.001) while treatment with both antidepressants and a mental health professional increased (p trend=0.002). Of the 286 (27.9%) depressed participants, between 43% and 69% did not receive depression treatment during any 18-month interval. 30.5% of the 121 participants with persistent depression did not receive treatment during the study period. Increasing number of years of education, decreasing cognitive status score, and being physically frail were associated with a higher likelihood of receiving treatment in all models. LIMITATIONS: Pre-baseline depression, pre-baseline treatment, and indication for treatment were unavailable.

conclusionsOur findings indicate that the profile of treatment for depression in older persons has changed over time, that depressed older persons, including those with persistent depression, are under-treated, and that patient characteristics influence receipt of treatment.

Indexed as

AgedAge FactorsAntidepressive AgentsDepressionFemaleHumansLongitudinal StudiesMalePsychotherapyAntidepressive Agents

Identifiers

PMID22030136
PMCPMC3272123
OpenAlexW1971088228

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.