ArticlePloS one2011
Efficient generation of iPS cells from skeletal muscle stem cells.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed.
- Transcriptomic atlas of premalignant oral squamous cell carcinoma in an aging mouse model reveals an enhanced immune response and dysregulation of head and neck tissue stem cells.bioRxiv : the preprint server for biology · 2026Article
- Single-cell analysis of bidirectional reprogramming between early embryonic states identify mechanisms of differential lineage plasticities in mice.Developmental cell · 2025Article
- Non-viral, Tumor-free Induction of Transient Cell Reprogramming in Mouse Skeletal Muscle to Enhance Tissue Regeneration.Molecular therapy : the journal of the American Society of Gene Therapy · 2019Article
- Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell Reprogramming.Stem cells international · 2019Review
- Diversity among POU transcription factors in chromatin recognition and cell fate reprogramming.Cellular and molecular life sciences : CMLS · 2018Review
- Skeletal Muscle Cell Induction from Pluripotent Stem Cells.Stem cells international · 2017Review
- Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.Experimental cell research · 2016Article
- Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle.The Journal of clinical investigation · 2015Article
- Positive correlation between the efficiency of induced pluripotent stem cells and the development rate of nuclear transfer embryos when the same porcine embryonic fibroblast lines are used as donor cells.Cellular reprogramming · 2014Article
- Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis.Arthritis research & therapy · 2014Article
- Combinatorial epigenetic patterns as quantitative predictors of chromatin biology.BMC genomics · 2014Article
- New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism.Cell metabolism · 2013Review
- Chromatin dynamics during cellular reprogramming.Nature · 2013Review
- Facile and efficient reprogramming of ciliary body epithelial cells into induced pluripotent stem cells.Stem cells and development · 2013Article
- Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.Cell reports · 2013Article
- Sources for skeletal muscle repair: from satellite cells to reprogramming.Journal of cachexia, sarcopenia and muscle · 2013Article
- Article
- Intrinsic ability of adult stem cell in skeletal muscle: an effective and replenishable resource to the establishment of pluripotent stem cells.Stem cells international · 2013Article
- Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles.Molecular therapy : the journal of the American Society of Gene Therapy · 2013Article
- A poor imitation of a natural process: a call to reconsider the iPSC engineering technique.Cell cycle (Georgetown, Tex.) · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Reprogramming of somatic cells into inducible pluripotent stem cells generally occurs at low efficiency, although what limits reprogramming of particular cell types is poorly understood. Recent data suggest that the differentiation status of the cell targeted for reprogramming may influence its susceptibility to reprogramming as well as the differentiation potential of the induced pluripotent stem (iPS) cells that are derived from it. To assess directly the influence of lineage commitment on iPS cell derivation and differentiation, we evaluated reprogramming in adult stem cell and mature cell populations residing in skeletal muscle. Our data using clonal assays and a second-generation inducible reprogramming system indicate that stem cells found in mouse muscle, including resident satellite cells and mesenchymal progenitors, reprogram with significantly greater efficiency than their more differentiated daughters (myoblasts and fibroblasts). However, in contrast to previous reports, we find no evidence of biased differentiation potential among iPS cells derived from myogenically committed cells. These data support the notion that adult stem cells reprogram more efficiently than terminally differentiated cells, and argue against the suggestion that "epigenetic memory" significantly influences the differentiation potential of iPS cells derived from distinct somatic cell lineages in skeletal muscle.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.