ArticleTropical medicine and health2011
A highly sensitive chemiluminescence assay for superoxide detection and chronic granulomatous disease diagnosis.
Article in Tropical medicine and health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Quantitative Assessment of Intracellular Effectors and Cellular Response in RAGE Activation.Archives of internal medicine research · 2024Article
- Chemical and Cellular Formation of Reactive Oxygen Species from Secondary Organic Aerosols in Epithelial Lining Fluid.Research report (Health Effects Institute) · 2023Article
- Superoxide Anion Chemistry-Its Role at the Core of the Innate Immunity.International journal of molecular sciences · 2023Review
- Superoxide Release by Macrophages through NADPH Oxidase Activation Dominating Chemistry by Isoprene Secondary Organic Aerosols and Quinones to Cause Oxidative Damage on Membranes.Environmental science & technology · 2022Article
- Effects of Acidity on Reactive Oxygen Species Formation from Secondary Organic Aerosols.ACS environmental Au · 2022Article
- Use of an Artificial Miniaturized Enzyme in Hydrogen Peroxide Detection by Chemiluminescence.Sensors (Basel, Switzerland) · 2020Article
- Perforin-2 Breaches the Envelope of Phagocytosed Bacteria Allowing Antimicrobial Effectors Access to Intracellular Targets.Journal of immunology (Baltimore, Md. : 1950) · 2018Article
- Chlamydia trachomatis paralyses neutrophils to evade the host innate immune response.Nature microbiology · 2018Article
- The Salmonella type-3 secretion system-1 and flagellar motility influence the neutrophil respiratory burst.PloS one · 2018Article
- Neuroprotection and antioxidants.Neural regeneration research · 2016Review
- Chemically synthesized molecules with the targeting and effector functions of antibodies.Journal of the American Chemical Society · 2014Article
- Oxidative stress-related biomarkers in essential hypertension and ischemia-reperfusion myocardial damage.Disease markers · 2013Review
- Effect of phenolic acids of microbial origin on production of reactive oxygen species in mitochondria and neutrophils.Journal of biomedical science · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reactive oxygen species (ROS) produced by neutrophils are crucial for defense against infectious diseases, and the adequate measurement of ROS levels is an important way to evaluate the possibility of infections. The fluorescent probe dihydrorhodamine 123 has been applied exclusively to the measurement of ROS thus far. We developed a novel method for detecting ROS, which utilizes the chemiluminescent probes Luminol and Diogenes. The new method quantitatively detects ROS produced by as few as 10 to 10(4) neutrophils. Furthermore, this method can detect ROS levels in one microliter of whole blood or ROS produced by Epstein-Barr immortalized B lymphocytes. This method will be valuable for prompt diagnosis of neonatal chronic granulomatous diseases in which neutrophils aberrantly produce superoxide.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.