Evidence map›Paper›PMID 22028340›Full record

ArticleStatistical methods in medical research2011

A frequentist approach to estimating the force of infection for a respiratory disease using repeated measurement data from a birth cohort.

H Mwambi, S Ramroop, Lj White, Ea Okiro, Dj Nokes, Z Shkedy, G Molenberghs

Abstract read
In one paragraph

Article in Statistical methods in medical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

H MwambiSchool of Statistics and Actuarial Science, University of KwaZulu-Natal, P/Bag X01, Scottsville, PMB, South Africa. MwambiH@ukzn.ac.za
S Ramroop
Lj White
Ea Okiro
Dj Nokes
Z Shkedy
G Molenberghs

Funding

Wellcome Trust 061584Wellcome Trust 076278
6 · The paper itself

Abstract

This article aims to develop a probability-based model involving the use of direct likelihood formulation and generalised linear modelling (GLM) approaches useful in estimating important disease parameters from longitudinal or repeated measurement data. The current application is based on infection with respiratory syncytial virus. The force of infection and the recovery rate or per capita loss of infection are the parameters of interest. However, because of the limitation arising from the study design and subsequently, the data generated only the force of infection is estimable. The problem of dealing with time-varying disease parameters is also addressed in the article by fitting piecewise constant parameters over time via the GLM approach. The current model formulation is based on that published in White LJ, Buttery J, Cooper B, Nokes DJ and Medley GF. Rotavirus within day care centres in Oxfordshire, UK: characterization of partial immunity. Journal of Royal Society Interface 2008; 5: 1481-1490 with an application to rotavirus transmission and immunity.

Indexed as

Cohort StudiesFemaleHumansMaleRespiratory Syncytial VirusesRespiratory Tract Infections

Identifiers

PMID22028340
PMCPMC3704207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.