Evidence map›Paper›PMID 22028278›Full record

ArticleDiabetes care2012

Combination of the Framingham risk score and carotid intima-media thickness improves the prediction of cardiovascular events in patients with type 2 diabetes.

Michiko Yoshida, Tomoya Mita, Risako Yamamoto, Tomoaki Shimizu, Fuki Ikeda, Chie Ohmura, Akio Kanazawa, Takahisa Hirose, Ryuzo Kawamori, Hirotaka Watada

Abstract read
In one paragraph

Article in Diabetes care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. State of the Art Review: Brachial-Ankle PWV.Journal of atherosclerosis and thrombosis · 2020
    Review
  12. Vascular Age as a Cardiovascular Risk Marker in Asymptomatic Patients with Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Observational
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michiko YoshidaDepartment of Medicine, Metabolism, and Endocrinology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tomoya Mita
Risako Yamamoto
Tomoaki Shimizu
Fuki Ikeda
Chie Ohmura
Akio Kanazawa
Takahisa Hirose
Ryuzo Kawamori
Hirotaka Watada

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate whether carotid intima-media thickness (IMT) and brachial-ankle pulse wave velocity (baPWV) add value to the Framingham risk score (FRS) in predicting the development of cardiovascular diseases (CVDs) in type 2 diabetic patients with a negative history of CVD. RESEARCH DESIGN AND

methodsType 2 diabetic patients (n = 783) were retrospectively recruited and followed for CVD.

resultsDuring a 5.4-year follow-up period, 85 incidences of CVD were recorded (10.9%). After adjustment for conventional arterial risk factors, multivariate analysis with the Cox proportional hazards model identified IMT, but not baPWV, as a significant determinant of CVD. In addition, the combination of FRS with IMT, but not with baPWV, improved the prediction of CVD.

conclusionsCarotid IMT is a significant predictor of CVD in asymptomatic type 2 diabetic patients, and the combination of FRS and IMT improves the prediction of CVD in these patients.

Indexed as

Ankle Brachial IndexCarotid Intima-Media ThicknessAdultAgedCardiovascular DiseasesDiabetes Mellitus, Type 2FemaleHumansJapanMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk Factors

Identifiers

PMID22028278
PMCPMC3241317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.