Evidence map›Paper›PMID 22027479›Full record

ArticleGut2012

Linking risk conferring mutations in NCF4 to functional consequences in Crohn's disease.

R Somasundaram, J J Deuring, C J van der Woude, M P Peppelenbosch, G M Fuhler

Abstract readLetterComment
PubMed Publisher
In one paragraph

Article in Gut, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Association between NCF4 rs4821544T/C polymorphism and inflammatory bowel disease risk in Caucasian: a meta-analysis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2015
    Pooled it
  3. Trial
  4. Article
  5. Modulatory Effects of Pregnancy on Inflammatory Bowel Disease.Clinical and translational gastroenterology · 2019
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Defects in NADPH Oxidase GenesCellular and molecular gastroenterology and hepatology · 2015
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

R Somasundaram
J J Deuring
C J van der Woude
M P Peppelenbosch
G M Fuhler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mutation, MissensePolymorphism, Single NucleotideCrohn DiseaseGranulomatous Disease, ChronicHumansInflammatory Bowel DiseasesNADPH OxidasesRAC2 GTP-Binding Proteinrac GTP-Binding ProteinsNADPH OxidasesNCF2 protein, humanRAC2 GTP-Binding Proteinrac GTP-Binding Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.