Evidence map›Paper›PMID 22027347›Full record

ArticleJournal of medical case reports2011

Multiple Scedosporium apiospermum abscesses in a woman survivor of a tsunami in northeastern Japan: a case report.

Yutaka Nakamura, Yu Utsumi, Naomi Suzuki, Yoshio Nakajima, Okinori Murata, Nobuhito Sasaki, Hiroo Nitanai, Hiromi Nagashima, Shinya Miyamoto, Jun Yaegashi and 8 more

Open access · goldAbstract read
In one paragraph

Article in Journal of medical case reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Invasive fungal infections after natural disasters.Emerging infectious diseases · 2014
    Pooled it
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  4. Climate Change Impacts on Environmental Fungi: Human Health and Fungal Disease.Current topics in microbiology and immunology · 2025
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  5. Review
  6. A Lateral-Flow Device for the Rapid Detection ofDiagnostics (Basel, Switzerland) · 2024
    Article
  7. Review
  8. SystemicInfection and drug resistance · 2024
    Article
  9. Article
  10. Review
  11. Update of occupational lung disease.Journal of occupational health · 2019
    Review
  12. Review
  13. Article
  14. Article
  15. Two cases of severe pneumonia after the 2011 Great East Japan Earthquake.Western Pacific surveillance and response journal : WPSAR · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Yutaka NakamuraDivision of Pulmonary Medicine, Allergy, and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine, 19-1 Uchimaru, Morioka, 0208505, Japan. ICB75097@nifty.com.
Yu Utsumi
Naomi Suzuki
Yoshio Nakajima
Okinori Murata
Nobuhito Sasaki
Hiroo Nitanai
Hiromi Nagashima
Shinya Miyamoto
Jun Yaegashi
Tomoki Hatakeyama
Yoshihiro Shibano
Kyoko Yarita
Katsuhiko Kamei
Toshihide Nakadate
Shigeatsu Endo
Yasuo Terayama
Kohei Yamauchi
Iwate Medical University · JPChiba University · JPIwate Prefectural Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionScedosporium apiospermum is increasingly recognized as a cause of localized and disseminated mycotic infections in near-drowning victims. CASE PRESENTATION: We report the case of a 59-year-old Japanese woman who was a survivor of a tsunami in northeastern Japan and who had lung and brain abscesses caused by S. apiospermum. Initially, an aspergillus infection was suspected, so she was treated with micafungin. However, computed tomography scans of her chest revealed lung abscesses, and magnetic resonance images demonstrated multiple abscesses in her brain. S. apiospermum was cultured from her bronchoalveolar lavage fluid, and antimycotic therapy with voriconazole was initiated. Since she developed an increase in the frequency of premature ventricular contractions, an adverse drug reaction to the voriconazole was suspected. She was started on a treatment of a combination of low-dose voriconazole and liposomal amphotericin B. After combination therapy, further computed tomography scans of the chest and magnetic resonance images of her brain showed a demarcation of abscesses.

conclusionsVoriconazole appeared to have a successful record in treating scedosporiosis after a near drowning but, owing to several adverse effects, may possibly not be recommended. Thus, a combination treatment of low-dose voriconazole and liposomal amphotericin B may be a safe and effective treatment for an S. apiospermum infection. Even though a diagnosis of scedosporiosis may be difficult, a fast and correct etiological diagnosis could improve the patient's chance of recovery in any case.

Identifiers

PMID22027347
PMCPMC3223506
OpenAlexW1985016099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.