ArticleBMC clinical pharmacology2011
What can we learn from consumer reports on psychiatric adverse drug reactions with antidepressant medication? Experiences from reports to a consumer association.
Article in BMC clinical pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02625155 (Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens), which is not on this map. Cited by 12 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Standard of Care Versus Urine Testing With Selective PHarmacogenomics for Effective Drug and Dosing REgimens: SPHERE
Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- Sex Differences in Reported Adverse Drug Reactions of Selective Serotonin Reuptake Inhibitors.Drug safety · 2018Article
- The Quality of Clinical Information in Adverse Drug Reaction Reports by Patients and Healthcare Professionals: A Retrospective Comparative Analysis.Drug safety · 2017Article
- Article
- Patient Participation and the Use of Ehealth Tools for Pharmacoviligance.Frontiers in pharmacology · 2016Review
- Pharmacovigilance from social media: mining adverse drug reaction mentions using sequence labeling with word embedding cluster features.Journal of the American Medical Informatics Association : JAMIA · 2015Article
- Consumer Narratives in ADR Reporting: An Important Aspect of Public Health? Experiences from Reports to a Swedish Consumer Organization.Frontiers in public health · 2015Article
- Reporting of drug induced depression and fatal and non-fatal suicidal behaviour in the UK from 1998 to 2011.BMC pharmacology & toxicology · 2014Article
- Adverse drug reactions reported by consumers for nervous system medications in Europe 2007 to 2011.BMC pharmacology & toxicology · 2013Article
- Side effects of antineoplastic and immunomodulating medications reported by European consumers.Journal of research in pharmacy practice · 2013Article
- A Pill for the Ill? Patients' Reports of Their Experience of the Medical Encounter in the Treatment of Depression.PloS one · 2013Article
- Experiences from consumer reports on psychiatric adverse drug reactions with antidepressant medication: a qualitative study of reports to a consumer association.BMC pharmacology & toxicology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccording to the World Health Organization (WHO) the cost of adverse drug reactions (ADRs) in the general population is high and under-reporting by health professionals is a well-recognized problem. Another way to increase ADR reporting is to let the consumers themselves report directly to the authorities. In Sweden it is mandatory for prescribers to report serious ADRs to the Medical Products Agency (MPA), but there are no such regulations for consumers. The non-profit and independent organization Consumer Association for Medicines and Health, KILEN has launched the possibility for consumers to report their perceptions and experiences from their use of medicines in order to strengthen consumer rights within the health care sector. This study aimed to analyze these consumer reports.
methodsAll reports submitted from January 2002 to April 2009 to an open web site in Sweden where anyone could report their experience with the use of pharmaceuticals were analyzed with focus on common psychiatric side effects related to antidepressant usage. More than one ADR for a specific drug could be reported.
resultsIn total 665 reports were made during the period. 442 reports concerned antidepressant medications and the individual antidepressant reports represented 2392 ADRs and 878 (37%) of these were psychiatric ADRs. 75% of the individual reports concerned serotonin-reuptake inhibitor (SSRI) and the rest serotonin-norepinephrine reuptake inhibitor (SNRI). Women reported more antidepressant psychiatric ADRs (71%) compared to men (24%). More potentially serious psychiatric ADRs were frequently reported to KILEN and withdrawal symptoms during discontinuation were also reported as a common issue.
conclusionsThe present study indicates that consumer reports may contribute with important information regarding more serious psychiatric ADRs following antidepressant treatment. Consumer reporting may be considered a complement to traditional ADR reporting.
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