ArticleJournal of the American Chemical Society2011
A new highly selective fluorescent K+ sensor.
Article in Journal of the American Chemical Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Localizable Fluorescent Metal Ion Indicators With Tunable Colors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Nanosensors for real-time intracellular analytics.Nature nanotechnology · 2025Review
- Sensitive red fluorescent indicators for real-time visualization of potassium ion dynamics in vivo.PLoS biology · 2025Article
- Decoding Potassium Homeostasis in Cancer Metastasis and Drug Resistance: Insights from a Highly Selective DNAzyme-Based Intracellular KJournal of the American Chemical Society · 2025Article
- A fluorescent ratiometric potassium sensor based on IPG4-silica microparticles for selective detection and fluorescence imaging of potassium cations.Journal of materials chemistry. B · 2024Article
- Bioluminescence Imaging of Potassium Ion Using a Sensory Luciferin and an Engineered Luciferase.Journal of the American Chemical Society · 2024Article
- Nanoscale potassium sensing based on valinomycin-anchored fluorescent gold nanoclusters.Mikrochimica acta · 2024Article
- A Simple Schiff Base Probe for Quintuplicate-Metal Analytes with Four Emission-Wavelength Responses.Molecules (Basel, Switzerland) · 2023Article
- Functional nucleic acid engineered double-barreled nanopores for measuring sodium to potassium ratio at single-cell level.Exploration (Beijing, China) · 2022Article
- A KNational science review · 2022Article
- Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids.Chemical reviews · 2022Review
- Electrochemical and Fluorescent Properties of Crown Ether Functionalized Graphene Quantum Dots for Potassium and Sodium Ions Detection.Nanomaterials (Basel, Switzerland) · 2021Article
- Vesicle-Based Sensors for Extracellular Potassium Detection.Cellular and molecular bioengineering · 2021Article
- Close Temporal Relationship between Oscillating Cytosolic KInternational journal of molecular sciences · 2020Article
- A highly sensitive and selective nanosensor for near-infrared potassium imaging.Science advances · 2020Article
- A sensitive and specific nanosensor for monitoring extracellular potassium levels in the brain.Nature nanotechnology · 2020Article
- Construction of a crystalline 14-metal Zn-Nd rectangular nanocluster with a dual-emissive response towards metal ions.RSC advances · 2019Article
- Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration.Communications biology · 2019Article
- Simultaneous Multiparameter Cellular Energy Metabolism Profiling of Small Populations of Cells.Scientific reports · 2018Article
- Nanoparticle-based fluoroionophore for analysis of potassium ion dynamics in 3D tissue models andAdvanced functional materials · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We describe the synthesis, properties, and application of a new fluorescent potassium chemosensor, KS2, for K(+) sensing and imaging in live cells. By virtue of a strong electron-withdrawing group, 2-dicyanomethylene-3-cyano-4,5,5-trimethyl-2,5-dihydrofuran (TCF), with a triazacryptand ligand, the new sensor can respond to K(+) up to 1.6 M. This is the first highly selective intracellular sensor suitable for sensing K(+) over a broad and high concentration range. Confocal fluorescence microscopy has established the utility of KS2 for live-cell K(+) detection. The application of KS2 combined with other sensors will be of great benefit for investigating cellular metabolism, detecting and diagnosing diseases including cancer, and monitoring responses to therapy.
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Registered trials
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