ArticleJournal of pharmacology & pharmacotherapeutics2011
A study of adverse drug reactions in pediatric patients.
Article in Journal of pharmacology & pharmacotherapeutics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 96 citations in OpenAlex.
- Comparative epidemiology of hospital-acquired adverse drug reactions in adults and children and their impact on cost and hospital stay--a systematic review.European journal of clinical pharmacology · 2013Pooled it
- Drug Manipulation in Pediatric Care: A Scoping Review of a Widespread Practice Signaling Systemic Gaps in Pharmaceutical Provision.Pharmacy (Basel, Switzerland) · 2025Review
- Antibiotic prophylaxis in pediatric dog bite injuries: Infection rates and prescribing practices.Journal of the American College of Emergency Physicians open · 2024Article
- Article
- Analysis of Adverse Drug Reactions in Pediatric Patients with Epilepsy: An Intensive Pharmacovigilance Study.Children (Basel, Switzerland) · 2023Article
- No population left behind: Improving paediatric drug safety using informatics and systems biology.British journal of clinical pharmacology · 2022Review
- Pediatric Adverse Drug Reactions: An Observational Cohort Study After Health Care Workers' Training.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2022Article
- Article
- The Burden of Preventable Adverse Drug Events on Hospital Stay and Healthcare Costs in Japanese Pediatric Inpatients: The JADE Study.Clinical medicine insights. Pediatrics · 2021Article
- Evaluation of Adverse Drug Reactions in Paediatric Patients: A Retrospective Study in Turkish Hospital.Frontiers in pharmacology · 2021Article
- Pharmacovigilance Reports Received from Children and Young People, and Development of Information to Aid Future Reporting from this Age Group.Paediatric drugs · 2020Article
- Suspected Overlap Between Serotonin Syndrome and Neuroleptic Malignant Syndrome in a Child Treated With Metoclopramide?The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2020Article
- Improvement in the Analysis of Vaccine Adverse Event Reporting System Database.Statistics in biopharmaceutical research · 2020Article
- A 7-Years Active Pharmacovigilance Study of Adverse Drug Reactions Causing Children Admission to a Pediatric Emergency Department in Sicily.Frontiers in pharmacology · 2020Article
- Induced pluripotent stem cells for therapy personalization in pediatric patients: Focus on drug-induced adverse events.World journal of stem cells · 2019Review
- Adverse Drug Events and Reactions Managed by Medical Toxicologists: an Analysis of the Toxicology Investigators Consortium (ToxIC) Registry, 2010-2016.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2019Article
- Naranjo Question Answering using End-to-End Multi-task Learning Model.KDD : proceedings. International Conference on Knowledge Discovery & Data Mining · 2019Article
- Clinical Judgement Study using Question Answering from Electronic Health Records.Proceedings of machine learning research · 2019Article
- Serious Adverse Events Associated with Off-Label Use of Azithromycin or Fentanyl in Children in Intensive Care Units: A Retrospective Chart Review.Paediatric drugs · 2019Article
- Characterization of serious adverse drug reactions as cause of emergency department visit in children: a 5-years active pharmacovigilance study.BMC pharmacology & toxicology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study the adverse drug reaction (ADR) pattern in a pediatric population in a tertiary care hospital. MATERIALS AND
methodsAn observational study was done in the department of pediatrics in a tertiary care hospital. The ADRs occurring in the inpatient wards and outpatient department of pediatrics were actively monitored. The collected reports were analyzed for ADR pattern, drug groups, demographic profile, causality, severity, and preventability of the ADR.
resultsA total of 30 ADRs were documented during the mid period of 2009 among pediatric patients. Most of the ADRs (60%) occurred below the age of 1 year. Antibiotics comprised the major group of drugs causing ADRs (67%). Rashes and urticaria were the most common type of ADR (37%) followed by fever, anaphylactic shock, vomiting, chills, and rigors. A single case of death had been reported in the study period. There were more occurrences of ADRs with multiple drugs compared to single drug therapy. About 80% of the ADRs were of probable causality and 87% were of probable preventability. There were no mild reactions, with 77% of reactions being moderate and 23% of reactions being severe in the severity scale.
conclusionsADRs occur more among infants and antibiotics were more commonly implicated. Most of the reactions were of moderate severity. This indicates the need for a rigid ADR monitoring among pediatric patients to ensure safety of drug therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.