Selective knockout of the vitamin d receptor in the heart results in cardiac hypertrophy: is the heart a drugable target for vitamin D receptor agonists?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

11 citing papers in PubMed.

1. Vitamin D and Cardiovascular Disease: The "Good", the "Bad", and the "Unknown".Reviews in cardiovascular medicine · 2025
   Review
2. The longevity-associated BPIFB4 gene supports cardiac function and vascularization in ageing cardiomyopathy.Cardiovascular research · 2023
   Article
3. Understanding the Role of Vitamin D in Heart Failure.Reviews in cardiovascular medicine · 2023
   Review
4. Vitamin D deficiency and functional response to CRT in heart failure patients.Herz · 2019
   Article
5. Lack of vitamin D signalling per se does not aggravate cardiac functional impairment induced by myocardial infarction in mice.PloS one · 2018
   Article
6. Fine tuning of vitamin D receptor (VDR) activity by post-transcriptional and post-translational modifications.Oncotarget · 2017
   Review
7. Vitamin D, Homocysteine, and Folate in Subcortical Vascular Dementia and Alzheimer Dementia.Frontiers in aging neuroscience · 2017
   Article
8. Optimal Vitamin D Supplementation Levels for Cardiovascular Disease Protection.Disease markers · 2015
   Review
9. Vitamin D and cardiovascular disease: is the evidence solid?European heart journal · 2013
   Review
10. Vitamin D signaling pathway plays an important role in the development of heart failure after myocardial infarction.Journal of applied physiology (Bethesda, Md. : 1985) · 2013
    Article
11. Vitamin D in Cardiovascular Disease.In vivo (Athens, Greece)
    Review

Corrections and comments

• Comment on
  Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy.2011

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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