ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2012
Childhood physical abuse and respiratory disease in the community: the role of mental health and cigarette smoking.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The long-term health consequences of child physical abuse, emotional abuse, and neglect: a systematic review and meta-analysis.PLoS medicine · 2012Pooled it
- The Many Faces of Child Abuse: How Clinical, Genetic and Epigenetic Correlates Help Us See the Full Picture.Children (Basel, Switzerland) · 2025Review
- Exposure to childhood maltreatment predicts adult physiological dysregulation, particularly inflammation.PloS one · 2023Article
- Assessment of Additional Medical Costs Among Older Adults in Japan With a History of Childhood Maltreatment.JAMA network open · 2020Article
- Adverse childhood experiences and chronic lung diseases in adulthood: a systematic review and meta-analysis.European journal of psychotraumatology · 2020Review
- Association of Reports of Childhood Abuse and All-Cause Mortality Rates in Women.JAMA psychiatry · 2016Article
- Alcohol and tobacco use among maltreated and non-maltreated adolescents in a birth cohort.Addiction (Abingdon, England) · 2014Article
- The Neurobiology of Panic: A Chronic Stress Disorder.Chronic stress (Thousand Oaks, Calif.)Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
introductionPrevious studies have found an association between child abuse and respiratory disease in some populations, but the mechanisms remain unknown, and this association has not been examined in a representative community-based sample. The goal of this study was to examine the relationship between childhood physical abuse and the odds of respiratory disease and to investigate the role of depression, anxiety, and pack-years of smoking in this association.
methodsData were drawn from the Midlife Development in the United States Survey (n = 3,032), a representative sample of adults aged 25-74 years. Multiple logistic regression analyses were used to determine the association between childhood abuse and current respiratory disease (past 12 months) and to examine whether pack-years of smoking, depression, and anxiety disorders mediated the relationship.
resultsIndividuals who often experienced childhood abuse had a significantly increased odds of respiratory disease (odds ratio [OR] = 1.87 [1.21, 2.90]). The association was attenuated, after adjusting for demographic characteristics and pack-years of smoking, and was no longer significant after adjusting for depression and anxiety disorders.
conclusionsThese results are consistent with previous data suggesting a significant association between childhood abuse and respiratory disease and extend existing knowledge by providing initial evidence that demographic differences, depression and anxiety disorders, and lifetime cigarette smoking may mediate this observed relationship. Results require replication with longitudinal data in large community-based samples. Future studies that can explore potential biological mechanisms underlying the observed associations, such as immune factors, are needed next to better understand these relationships.
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