Chlorthalidone versus hydrochlorothiazide: a tale of tortoises and a hare.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

9 citing papers in PubMed.

1. Advances in the Treatment Strategies in Hypertension: Present and Future.Journal of cardiovascular development and disease · 2022
   Review
2. Thiazide diuretics alone or in combination with a potassium-sparing diuretic on blood pressure-lowering in patients with primary hypertension: protocol for a systematic review and network meta-analysis.Systematic reviews · 2022
   Article
3. Indian guidelines on hypertension-IV (2019): need to differentiate thiazide-like diuretics.Journal of human hypertension · 2020
   Article
4. Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension: a protocol for a factorial randomized controlled trial.Trials · 2019
   Article
5. Not just chlorthalidone: evidence-based, single tablet, diuretic alternatives to hydrochlorothiazide for hypertension.Current hypertension reports · 2015
   Article
6. Comparing clinical effectiveness and drug toxicity with hydrochlorothiazide and chlorthalidone using two potency ratios in a managed care population.Journal of clinical hypertension (Greenwich, Conn.) · 2015
   Article
7. A 91-year-old woman with difficult-to-control hypertension: a clinical review.JAMA · 2013
   Review
8. Which diuretic is the preferred agent for treating essential hypertension: hydrochlorothiazide or chlorthalidone?Current cardiology reports · 2012
   Review
9. Effects of antihypertensive drugs on arterial stiffness.Cardiology in review
   Review

Corrections and comments

• Comment on
  Long-term effects of chlorthalidone versus hydrochlorothiazide on electrocardiographic left ventricular hypertrophy in the multiple risk factor intervention trial.2011

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as