Evidence map›Paper›PMID 22025249›Full record

ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2012

Gender and condylar differences in distal femur morphometry clarified by automated computer analyses.

Kang Li, Evan Langdale, Scott Tashman, Christopher Harner, Xudong Zhang

Abstract read
In one paragraph

Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The inclination of the femoral medial posterior condyle was almost vertical and that of the lateral was tilted medially.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Gender differences in morphology exist in posterior condylar offsets of the knee in Korean population.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
    Article
  11. The C-reactive protein level after total knee arthroplasty is gender specific.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016
    Article
  12. Article
  13. No sex differences exist in posterior condylar offsets of the knee.Clinical orthopaedics and related research · 2015
    Article
  14. The surgical epicondylar axis is a consistent reference of the distal femur in the coronal and axial planes.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014
    Article
  15. Gender differences in the morphology of the trochlea and the distal femur.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2014
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kang LiDepartment of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Evan Langdale
Scott Tashman
Christopher Harner
Xudong Zhang
University of Pittsburgh · USRutgers, The State University of New Jersey · US

Funding

DYNAMIC KNEE STABILITY AFTER ACL RECONSTRUCTIONR01AR046387 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TASHMAN, SCOTT · 1999 to 2009
$2.5M
A computer modeling tool for optimizing Meniscus Allograft TransplantationR03AR059939 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ZHANG, XUDONG · 2010 to 2012
$221k
NIAMS NIH HHS 3R01AR046387-10S1NIAMS NIH HHS R01 AR046387NIAMS NIH HHS R03 AR059939
6 · The paper itself

Abstract

We elucidated the gender and condylar effects on distal femur morphology (DFM) while evaluating a newly developed computational framework that enables fully automated analyses of DFM in an objectively defined sagittal plane. Ninety high-resolution CT-acquired distal femur models from 51 males and 39 females were analyzed. The models were accurately characterized (mean least-squares fitting residual <0.16 mm), and re-oriented to a unified sagittal plane; three morphometric measures were extracted from each model: the semi-major (a) and semi-minor (b) axis lengths of the best-fitted ellipse, and the radius (r) of the smallest flexion facet-a circle with the smallest radius best-fitted to the posterior articulating surface. Statistical analyses employing nonparametric repeated-measures ANOVA found: no significance difference between condyles or between limbs in any of the morphometric measures; significant gender effects on a, b, and r, but no gender effect on the aspect ratio (a/b). An inspection of statistical distributions of medial-lateral condyle size differences also revealed a gender difference. The findings promote a better understanding of DFM and its relation to knee mechanics and have implications on computer-aided surgery of the knee and gender-specific implant design.

Indexed as

Sex CharacteristicsAlgorithmsFemaleFemurHumansImaging, Three-DimensionalMaleRadiographyReference Values

Identifiers

PMID22025249
PMCPMC3290733
OpenAlexW2011291194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.