Evidence map›Paper›PMID 22024949›Full record

Trial reportThe journals of gerontology. Series A, Biological sciences and medical sciences2012

Effects of a 12-month physical activity intervention on prevalence of metabolic syndrome in elderly men and women.

Xuewen Wang, Fang-Chi Hsu, Scott Isom, Michael P Walkup, Stephen B Kritchevsky, Bret H Goodpaster, Timothy S Church, Marco Pahor, Randall S Stafford, Barbara J Nicklas

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The journals of gerontology. Series A, Biological sciences and medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Walking for hypertension.The Cochrane database of systematic reviews · 2021
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Self-efficacy and Physical Activity in Overweight and Obese Adults Participating in a Worksite Weight Loss Intervention: Multistate Modeling of Wearable Device Data.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Trial
  6. Trial
  7. Observational
  8. Article
  9. Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome.Pediatric gastroenterology, hepatology & nutrition · 2020
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Xuewen WangDivision of Geriatrics and Nutritional Science, Washington University School of Medicine, St. Louis, MO 63110, USA. xwang@dom.wustl.edu
Fang-Chi Hsu
Scott Isom
Michael P Walkup
Stephen B Kritchevsky
Bret H Goodpaster
Timothy S Church
Marco Pahor
Randall S Stafford
Barbara J Nicklas
Wake Forest University · USPennington Biomedical Research Center · USStanford Health Care · USUniversity of Florida · USUniversity of Pittsburgh · USWashington University in St. Louis · US

Funding

UF FIELD CENTERU01AG022376 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI PAHOR, MARCO · 2003 to 2015
$83.3M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
UF CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR029890 · NCRR · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2009 to 2011
$14.4M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
ENERGY EXPENDITURE RESPONSES TO ACUTE AND CHRONIC EXERCISE IN OLDER WOMENK99AG031297 · NIA · WASHINGTON UNIVERSITY · PI WANG, XUEWEN · 2009 to 2010
$158k
Intramural NIH HHSNCATS NIH HHS UL1 TR000064NCRR NIH HHS UL1 RR029890NIA NIH HHS K99 AG031297NIA NIH HHS K99AG031297NIA NIH HHS P30 AG028740NIA NIH HHS U01 AG022376NIA NIH HHS U01 AG22376
6 · The paper itself

Abstract

backgroundThere is a lack of information on whether exercise training alone can reduce the prevalence of metabolic syndrome (MetS) in elderly men and women.

methodsThis study was an ancillary to the Lifestyle Interventions and Independence for Elders Pilot Study, a four-site, single-blind, randomized controlled clinical trial comparing a 12-month physical activity (PA) intervention (N = 180) with a successful aging intervention (N = 181) in elderly (70-89 years) community-dwelling men and women at risk for physical disability. The PA intervention included aerobic, strength, and flexibility exercises, with walking as the primary mode. MetS was defined using the National Cholesterol Education Program criteria.

resultsThere was no significant change in body weight or fat mass after either intervention. The trend of MetS prevalence over the intervention period was similar between PA and successful aging groups (p = .77). Overall, the prevalence of MetS decreased significantly from baseline to 6 months (p = .003) but did not change further from 6- to 12-month visits (p = .11). There were no group differences in any individual MetS components (p > .05 for all group by visit interactions). However, in individuals not using medications at any visit to treat MetS components, those in the PA intervention had lower odds of having MetS than those in the successful aging group during follow-up (odds ratio = 0.28, 95% confidence interval = 0.08-0.96).

conclusionsIn this sample, a 12-month PA intervention did not reduce the prevalence of MetS more than a successful aging intervention, perhaps due to the large proportion of individuals taking medications for treating MetS components.

Indexed as

Motor ActivityAdiposityAgedAged, 80 and overBody WeightFemaleHumansMaleMetabolic SyndromePilot ProjectsPrevalenceSingle-Blind MethodWalking

Identifiers

PMID22024949
PMCPMC3309873
OpenAlexW2108521409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.