ArticleJournal of clinical bioinformatics2011
Role of clinical bioinformatics in the development of network-based Biomarkers.
Article in Journal of clinical bioinformatics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
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- Bioinformatics in Early Cancer Detection.Cureus · 2023Review
- Development of cancer prognostic signature based on pan-cancer proteomics.Bioengineered · 2020Article
- Pan-cancer mapping of differential protein-protein interactions.Scientific reports · 2020Article
- Network spectra for drug-target identification in complex diseases: new guns against old foes.Applied network science · 2018Review
- Network Biomarkers Constructed from Gene Expression and Protein-Protein Interaction Data for Accurate Prediction of Leukemia.Journal of Cancer · 2017Article
- Identifying new targets in leukemogenesis using computational approaches.Saudi journal of biological sciences · 2015Article
- Pathway mapping and development of disease-specific biomarkers: protein-based network biomarkers.Journal of cellular and molecular medicine · 2015Review
- Dynamic gene expressions of peripheral blood mononuclear cells in patients with acute exacerbation of chronic obstructive pulmonary disease: a preliminary study.Critical care (London, England) · 2014Article
- Enhanced frequency and potential mechanism of B regulatory cells in patients with lung cancer.Journal of translational medicine · 2014Article
- Single-cell transcriptome in the identification of disease biomarkers: opportunities and challenges.Journal of translational medicine · 2014Article
- The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment.Journal of cellular and molecular medicine · 2014Article
- Network biomarkers, interaction networks and dynamical network biomarkers in respiratory diseases.Clinical and translational medicine · 2014Review
- Gene polymorphisms and chronic obstructive pulmonary disease.Journal of cellular and molecular medicine · 2014Article
- Respiratory diseases call for special attention from clinical and translational science.Translational respiratory medicine · 2013Article
- Article
- Opportunities and challenges of disease biomarkers: a new section in the Journal of Translational Medicine.Journal of translational medicine · 2012Article
- Opportunities and challenges of disease biomarkers: a new section in the Journal of Translational Medicine.Journal of translational medicine · 2012Article
- Development and promotion in translational medicine: perspectives from 2012 sino-american symposium on clinical and translational medicine.Clinical and translational medicine · 2012Article
Corrections and comments
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Authors and funding
1 author.
Funding
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Abstract
Network biomarker as a new type of biomarkers with protein-protein interactions was initiated and investigated with the integration of knowledge on protein annotations, interaction, and signaling pathway. A number of methodologies and computational programs have been developed to integrate selected proteins into the knowledge-based networks via the combination of genomics, proteomics and bioinformatics. Alterations of network biomarkers can be monitored and evaluated at different stages and time points during the development of diseases, named dynamic network biomarkers. Dynamic network biomarkers should be furthermore correlated with clinical informatics, including patient complaints, history, therapies, clinical symptoms and signs, physician's examinations, biochemical analyses, imaging profiles, pathologies and other measurements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.