Evidence map›Paper›PMID 22024003›Full record

Trial reportJournal of the American Academy of Child and Adolescent Psychiatry2011

Controlled comparison of family cognitive behavioral therapy and psychoeducation/relaxation training for child obsessive-compulsive disorder.

John Piacentini, R Lindsey Bergman, Susanna Chang, Audra Langley, Tara Peris, Jeffrey J Wood, James McCracken

Registry-linked trialOpen access · greenAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Academy of Child and Adolescent Psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00000386 (Behavior Therapy for Childhood OCD), which is not on this map. Cited by 86 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 7 pooled it
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00000386 phase3completednot on this map

Behavior Therapy for Childhood OCD

TypeinterventionalSponsorNational Institute of Mental Health (NIMH)Ran1998 to 2003ConditionsObsessive-Compulsive DisorderArmsExposure and Response Prevention, Family Treatment Program, Relaxation Training, Behavior therapy, Family Counseling
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 7 syntheses or guidelines pooled it, 288 citations in OpenAlex.

  1. Pooled it
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  3. Relaxation therapy as a treatment for tics in patients with Tourette syndrome: a systematic literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Pooled it
  4. Pooled it
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  6. Assessment and management of treatment-refractory obsessive-compulsive disorder in children.Journal of the American Academy of Child and Adolescent Psychiatry · 2015
    Pooled it
  7. Family involvement in the psychological treatment of obsessive-compulsive disorder: a meta-analysis.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2014
    Pooled it
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  14. Quality of Life in Children and Youth with Obsessive-Compulsive Disorder.Journal of child and adolescent psychopharmacology · 2018
    Trial
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  16. Glutamate in Pediatric Obsessive-Compulsive Disorder and Response to Cognitive-Behavioral Therapy: Randomized Clinical Trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017
    Trial
  17. A Randomized Clinical Trial of an Integrative Group Therapy for Children With Severe Mood Dysregulation.Journal of the American Academy of Child and Adolescent Psychiatry · 2016
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

John PiacentiniUniversity of California-Los Angeles Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA 90024, USA. jpiacentini@mednet.ucla.edu
R Lindsey Bergman
Susanna Chang
Audra Langley
Tara Peris
Jeffrey J Wood
James McCracken
University of California, Los Angeles · US

Funding

BEHAVIOR THERAPY FOR CHILDHOOD OCDR01MH058459 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PIACENTINI, JOHN C. · 1999 to 2002
$1.0M
NIMH NIH HHS R01 MH058459NIMH NIH HHS R01MH58549-01
6 · The paper itself

Abstract

objectiveTo examine the efficacy of exposure-based cognitive-behavioral therapy (CBT) plus a structured family intervention (FCBT) versus psychoeducation plus relaxation training (PRT) for reducing symptom severity, functional impairment, and family accommodation in youths with obsessive-compulsive disorder (OCD).

methodA total of 71 youngsters 8 to 17 years of age (mean 12.2 years; range, 8-17 years, 37% male, 78% Caucasian) with primary OCD were randomized (70:30) to 12 sessions over 14 weeks of FCBT or PRT. Blind raters assessed outcomes with responders followed for 6 months to assess treatment durability.

resultsFCBT led to significantly higher response rates than PRT in ITT (57.1% vs 27.3%) and completer analyses (68.3% vs. 35.3%). Using HLM, FCBT was associated with significantly greater change in OCD severity and child-reported functional impairment than PRT and marginally greater change in parent-reported accommodation of symptoms. These findings were confirmed in some, but not all, secondary analyses. Clinical remission rates were 42.5% for FCBT versus 17.6% for PRT. Reduction in family accommodation temporally preceded improvement in OCD for both groups and child functional status for FCBT only. Treatment gains were maintained at 6 months.

conclusionsFCBT is effective for reducing OCD severity and impairment. Importantly, treatment also reduced parent-reported involvement in symptoms with reduced accommodation preceding reduced symptom severity and functional impairment. CLINICAL TRIALS REGISTRY INFORMATION: Behavior Therapy for Children and Adolescents with Obsessive-Compulsive Disorder (OCD); http://www.clinicaltrials.gov; NCT00000386.

Indexed as

Cognitive Behavioral TherapyFamily TherapyRelaxation TherapyAdolescentChildCombined Modality TherapyFemaleHumansImplosive TherapyMaleObsessive-Compulsive DisorderParentsPsychiatric Status Rating ScalesSeverity of Illness IndexSingle-Blind MethodTreatment Outcome

Identifiers

PMID22024003
PMCPMC3205429
OpenAlexW2121070134

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.