ArticlePloS one2011
Prevalence and risk factors associated to chronic kidney disease in HIV-infected patients on HAART and undetectable viral load in Brazil.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Kidney dysfunction and associated factors among adults living with human immuno-deficiency virus in Africa: a systematic review and meta-analysis.BMC nephrology · 2025Pooled it
- Prevalence and burden of chronic kidney disease among the general population and high-risk groups in Africa: a systematic review.BMJ open · 2018Pooled it
- Chronic kidney disease in the global adult HIV-infected population: A systematic review and meta-analysis.PloS one · 2018Pooled it
- Prevalence and determinants of chronic kidney disease among HIV/AIDS patients in selected governmental hospitals at Addis Ababa, Ethiopia: a retrospective cross-sectional study.BMC infectious diseases · 2025Article
- Article
- Chronic kidney disease and its associated factors in HIV-infected individuals: a comparison of antiretroviral therapy naïve and experienced patients.Frontiers in medicine · 2024Article
- Chronic kidney disease and its predictors among highly active antiretroviral therapy naïve and experienced HIV-infected individuals at the selected hospitals, Southwest Ethiopia: a comparative cross-sectional study.BMJ public health · 2023Article
- Factors Associated with Antiretroviral Therapy Toxicity Out-Comes in Patients with and without Hypertension.International journal of environmental research and public health · 2022Article
- Contributory role of ART in the development of non-AIDS comorbidities in asymptomatic PLWHA.Journal of applied biomedicine · 2021Article
- Renal Function Impairment and Associated Factors Among Adult HIV-Positive Patients Attending Antiretroviral Therapy Clinic in Mettu Karl Referral Hospital: Cross-Sectional Study.HIV/AIDS (Auckland, N.Z.) · 2021Article
- Chronic Kidney Disease and Associated Factors Among HIV/AIDS Patients on HAART in Ethiopia.HIV/AIDS (Auckland, N.Z.) · 2020Article
- HIV and kidney diseases: 35 years of history and consequences.Clinical kidney journal · 2016Review
- Tenofovir-induced nephrotoxicity: incidence, mechanism, risk factors, prognosis and proposed agents for prevention.European journal of clinical pharmacology · 2014Review
- Tenofovir effect on the kidneys of HIV-infected patients: a double-edged sword?Journal of the American Society of Nephrology : JASN · 2013Review
- Association between antiretroviral exposure and renal impairment among HIV-positive persons with normal baseline renal function: the D:A:D study.The Journal of infectious diseases · 2013Article
- WHO antiretroviral therapy guidelines 2010 and impact of tenofovir on chronic kidney disease in Vietnamese HIV-infected patients.PloS one · 2013Article
- Clinical outcomes of a combined HIV and renal clinic.Clinical kidney journal · 2012Article
- Prevalence of proteinuria and elevated serum cystatin C among HIV-Infected Adolescents in the Reaching for Excellence in Adolescent Care and Health (REACH) study.Journal of acquired immune deficiency syndromes (1999) · 2012Article
- Comparisons between validated estimated glomerular filtration rate equations and isotopic glomerular filtration rate in HIV patients.AIDS (London, England) · 2012Article
- HIV therapies and the kidney: some good, some not so good?Current HIV/AIDS reports · 2012Review
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6 authors.
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Abstract
backgroundTo determine the prevalence and associated factors with chronic kidney disease (CKD) in a cohort of HIV-positive individuals with undetectable viral load on HAART.
methodsFrom March, 2009 to September 2009, 213 individuals between 18-70 years, period on HAART ≥12 months, viral load < 50 copies/mm(3), and CD4 ≥ 200 cells/mm(3), were consecutively enrolled at the outpatient clinic of Hospital de Clínicas, Porto Alegre, Brazil. Exclusion criteria were obesity, malnourishment, amputee, paraplegic, previous history of renal disease, pregnancy and hepatic insufficiency. Renal function was determined by estimated glomerular filtration rate (eGFR) assessed by the modification of diet in renal disease. CKD was defined as an eGFR less or equal than 60 ml/min/1.73 m(2), for a period of at least 3 months. Poisson regression was used to determine factors associated with CKD.
resultsCKD was diagnosed in 8.4% of the population, and after adjustment, the risk factors were hypertension (RR = 3.88, 95%CI, 1.84-8.16), time on HAART (RR = 1.15, 95%CI,1.03-1.27) and tenofovir exposure (RR = 2.25, 95%CI, 1.04-4.95). Higher weight (RR = 0.88 95%CI, 0.82-0.96) was associated to normal function.
conclusionsCKD was a common finding in this cohort of patients and was related to hypertension, time on HAART and tenofovir exposure. We suggest a more frequent monitoring of renal function, especially for those with risk factors to early identify renal impairment.
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