ArticlePLoS pathogens2011
Endophytic life strategies decoded by genome and transcriptome analyses of the mutualistic root symbiont Piriformospora indica.
Article in PLoS pathogens, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.
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149 citing papers in PubMed, 435 citations in OpenAlex.
- Comparative analysis towards the identification of genome wide characteristics of a beneficial fungal endophyte.Scientific reports · 2026Article
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- Cross-talk within plant niches: endophytic and arbuscular mycorrhizal fungi for sustainable crop production.FEMS microbiology reviews · 2026Review
- Lyophilized Preparation of Root Endophyte FungusInternational journal of microbiology · 2026Article
- Autophagy restricts symbiosis-associated cell death and regulates colonization by Serendipita indica in Arabidopsis.Plant physiology · 2025Article
- Comparative Symbiotic Effects of Mycorrhizal Fungal Strains from Different Hosts on Seed Germination and Seedling Growth inJournal of fungi (Basel, Switzerland) · 2025Article
- The effect of arbuscular mycorrhizal fungi on the growth of wheat seedlings with contrasting phosphorus use efficiencies under low phosphorus stress.BMC plant biology · 2025Article
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- A pipeline for validation of Serendipita indica effector-like sRNA suggests cross-kingdom communication in the symbiosis with Arabidopsis.Journal of experimental botany · 2025Article
- The Three-Dimensional Structure of the Genome of the Dark Septate EndophyteJournal of fungi (Basel, Switzerland) · 2025Article
- Closed Systems to Study Plant-Filamentous Fungi Associations: Emphasis on Microscopic Analyses.Bio-protocol · 2025Article
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- Isolation and characterization of a new Leptobacillium species promoting tomato plant growth.Scientific reports · 2025Article
- Adoption of a novel medium for the industrial (3000 L) production of Serendipita indica employing a nutrient limitation strategy using insoluble carbon and phosphate sources.Journal of industrial microbiology & biotechnology · 2024Article
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- In silico analysis of fungal prion-like proteins for elucidating their role in plant-fungi interactions.Archives of microbiology · 2024Article
- CgNis1's Impact on Virulence and Stress Response inInternational journal of molecular sciences · 2024Article
- Isolation and characterization of a newly discovered plant growth-promoting endophytic fungal strain from the genus Talaromyces.Scientific reports · 2024Article
- Nutrient and mycoremediation of a global menace 'arsenic': exploring the prospects of phosphorus and Serendipita indica-based mitigation strategies in rice and other crops.Plant cell reports · 2024Review
- Ammonia leakage can underpin nitrogen-sharing among soil microorganisms.The ISME journal · 2024Article
89 more citing papers are in PubMed but not listed here.
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent sequencing projects have provided deep insight into fungal lifestyle-associated genomic adaptations. Here we report on the 25 Mb genome of the mutualistic root symbiont Piriformospora indica (Sebacinales, Basidiomycota) and provide a global characterization of fungal transcriptional responses associated with the colonization of living and dead barley roots. Extensive comparative analysis of the P. indica genome with other Basidiomycota and Ascomycota fungi that have diverse lifestyle strategies identified features typically associated with both, biotrophism and saprotrophism. The tightly controlled expression of the lifestyle-associated gene sets during the onset of the symbiosis, revealed by microarray analysis, argues for a biphasic root colonization strategy of P. indica. This is supported by a cytological study that shows an early biotrophic growth followed by a cell death-associated phase. About 10% of the fungal genes induced during the biotrophic colonization encoded putative small secreted proteins (SSP), including several lectin-like proteins and members of a P. indica-specific gene family (DELD) with a conserved novel seven-amino acids motif at the C-terminus. Similar to effectors found in other filamentous organisms, the occurrence of the DELDs correlated with the presence of transposable elements in gene-poor repeat-rich regions of the genome. This is the first in depth genomic study describing a mutualistic symbiont with a biphasic lifestyle. Our findings provide a significant advance in understanding development of biotrophic plant symbionts and suggest a series of incremental shifts along the continuum from saprotrophy towards biotrophy in the evolution of mycorrhizal association from decomposer fungi.
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