Evidence map›Paper›PMID 22022003›Full record

ArticleIndian journal of pharmacology2011

Anti-anxiety activity of Coriandrum sativum assessed using different experimental anxiety models.

Poonam Mahendra, Shradha Bisht

Abstract read
In one paragraph

Article in Indian journal of pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Evaluating the effect ofMedical journal of the Islamic Republic of Iran · 2020
    Article
  7. Neuroprotective potency of some spice herbs, a literature review.Journal of traditional and complementary medicine · 2019
    Review
  8. Effects of DCM Leaf Extract ofBehavioural neurology · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Evaluation of antioxidant effect ofIndian journal of pharmacology
    Article
  14. Preventive effect ofAvicenna journal of phytomedicine
    Article
  15. Effects ofAvicenna journal of phytomedicine
    Article
  16. In Vivo Psychopharmacological Investigation ofBasic and clinical neuroscience
    Article
  17. Neuroprotective effects ofAvicenna journal of phytomedicine
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Poonam MahendraDepartment of Pharmacology, School of Pharmacy, Suresh Gyan Vihar University, Jaipur - 302 004, India.
Shradha Bisht

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interest in alternative medicine and plant-derived medications that affect the "mind" is growing. The aim of present study was to explore the anti-anxiety activity of hydroalcoholic extract of Coriandrum sativum (Linn.) using different animal models (elevated plus maze, open field test, light and dark test and social interaction test) of anxiety in mice. Diazepam (0.5 mg/kg) was used as the standard and dose of hydroalcoholic extract of C. sativum fruit (50, 100 and 200 mg/kg) was selected as per OECD guidelines. Results suggested that extract of C. sativum at 100 and 200 mg/kg dose produced anti-anxiety effects almost similar to diazepam, and at 50 mg/kg dose did not produce anti-anxiety activity on any of the paradigm used. Further studies are needed to identify the anxiolytic mechanism(s) and the phytoconstituents responsible for the observed central effects of the hydroalcoholic extract of C. sativum.

Indexed as

Coriandrum sativum (Linn.)elevated plus mazelight and dark testopen field testsocial interaction test

Identifiers

PMID22022003
PMCPMC3195130

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.