Evidence map›Paper›PMID 22021757›Full record

ArticleBMJ open2011

Yoga respiratory training improves respiratory function and cardiac sympathovagal balance in elderly subjects: a randomised controlled trial.

Danilo F Santaella, Cesar R S Devesa, Marcos R Rojo, Marcelo B P Amato, Luciano F Drager, Karina R Casali, Nicola Montano, Geraldo Lorenzi-Filho

3 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 50 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 4 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00969345 phase3completednot on this map

Effects of Respiratory Yoga Training (Bhastrika) on Heart Rate Variability and Baroreflex, and Quality of Life of Healthy Elderly Subjects

TypeinterventionalSponsorUniversity of Sao PauloRan2007 to 2008Enrolled30ConditionsElderly Subjects, Respiration ExercisesArmsStretching Exercises, Respiratory Exercises conducted twice a day for 10 minutes
NCT02539524 nacompletednot on this mapstarted 2015, after this paper: background citation

Effects of Yoga Respiratory Exercises on Clinical Impact, and Psychosocial Aspects in Patients With Chronic Obstructive Pulmonary Disease

TypeinterventionalSponsorUniversity of Sao PauloRan2015 to 2015Enrolled18ConditionsChronic Pulmonary Obstructive DiseaseArmsYoga bhastrika pranayama breathing exercise, Pulmonary Rehabilitation
NCT03227393 nawithdrawnnot on this mapstarted 2017, after this paper: background citation

The Effect of Yoga on Cardiac Sympathetic Innervation Evaluated by I-123 mIBG

TypeinterventionalSponsorUniversity of CincinnatiRan2017 to 2017Enrolled0ConditionsHeart Failure, SystolicArmsYoga training
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 4 syntheses or guidelines pooled it, 137 citations in OpenAlex.

  1. Pooled it
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  12. Time sequence of autonomic changes induced by daily slow-breathing sessions.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2015
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  14. Blood pressure and Purdue pegboard scores in individuals with hypertension after alternate nostril breathing, breath awareness, and no intervention.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Trial
  15. Trial
  16. Article
  17. Review
  18. Safety, feasibility and impact of a 12-week yoga program in adults Fontan patients: a pilot study.International journal of cardiology. Congenital heart disease · 2026
    Article
  19. Association Between Carotid Arterial Strain and Heart Rate Variability in Older Age.Journal of clinical hypertension (Greenwich, Conn.) · 2026
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Danilo F SantaellaSleep Laboratory, Pneumology Division, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, Brazil.
Cesar R S Devesa
Marcos R Rojo
Marcelo B P Amato
Luciano F Drager
Karina R Casali
Nicola Montano
Geraldo Lorenzi-Filho
Universidade de São Paulo · BRLuigi Sacco Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesSince ageing is associated with a decline in pulmonary function, heart rate variability and spontaneous baroreflex, and recent studies suggest that yoga respiratory exercises may improve respiratory and cardiovascular function, we hypothesised that yoga respiratory training may improve respiratory function and cardiac autonomic modulation in healthy elderly subjects.

design76 healthy elderly subjects were enrolled in a randomised control trial in Brazil and 29 completed the study (age 68 ± 6 years, 34% males, body mass index 25 ± 3 kg/m²). Subjects were randomised into a 4-month training program (2 classes/week plus home exercises) of either stretching (control, n=14) or respiratory exercises (yoga, n=15). Yoga respiratory exercises (Bhastrika) consisted of rapid forced expirations followed by inspiration through the right nostril, inspiratory apnoea with generation of intrathoracic negative pressure, and expiration through the left nostril. Pulmonary function, maximum expiratory and inspiratory pressures (PE(max) and PI(max), respectively), heart rate variability and blood pressure variability for spontaneous baroreflex determination were determined at baseline and after 4 months.

resultsSubjects in both groups had similar demographic parameters. Physiological variables did not change after 4 months in the control group. However, in the yoga group, there were significant increases in PE(max) (34%, p<0.0001) and PI(max) (26%, p<0.0001) and a significant decrease in the low frequency component (a marker of cardiac sympathetic modulation) and low frequency/high frequency ratio (marker of sympathovagal balance) of heart rate variability (40%, p<0.001). Spontaneous baroreflex did not change, and quality of life only marginally increased in the yoga group.

conclusionRespiratory yoga training may be beneficial for the elderly healthy population by improving respiratory function and sympathovagal balance. Trial Registration CinicalTrials.gov identifier: NCT00969345; trial registry name: Effects of respiratory yoga training (Bhastrika) on heart rate variability and baroreflex, and quality of life of healthy elderly subjects.

Identifiers

PMID22021757
PMCPMC3191432
OpenAlexW2134609944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.