ArticleJournal of the American Society of Nephrology : JASN2011
Growth in very young children undergoing chronic peritoneal dialysis.
Article in Journal of the American Society of Nephrology : JASN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
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Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Energy and protein requirements for children with CKD stages 2-5 and on dialysis-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2020Guideline
- Clinical practice recommendations for growth hormone treatment in children with chronic kidney disease.Nature reviews. Nephrology · 2019Guideline
- Clinical practice recommendations for the care of infants with stage 5 chronic kidney disease (CKD5).Pediatric nephrology (Berlin, Germany) · 2013Guideline
- Efficacy and safety of sevelamer carbonate in hyperphosphatemic pediatric patients with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2018Trial
- The impact of nutritional management on the growth and nutritional status of children on regular hemodialysis.Pediatric nephrology (Berlin, Germany) · 2026Article
- Long-term need and potential for withdrawal of enteral feeding in children with chronic kidney disease stage 5D or 5T.Clinical and experimental nephrology · 2025Article
- Diagnosis and management of mineral and bone disorders in infants with CKD: clinical practice points from the ESPN CKD-MBD and Dialysis working groups and the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2023Review
- Nutritional management of the infant with chronic kidney disease stages 2-5 and on dialysis.Pediatric nephrology (Berlin, Germany) · 2023Review
- Care of the pediatric patient on chronic peritoneal dialysis.Pediatric nephrology (Berlin, Germany) · 2022Article
- Longitudinal outcomes of body mass index in overweight and obese children with chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Efficacy of intradialytic amino acids on nutritional status in children with stage 5 chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2021Article
- Targeting optimal PD management in children: what have we learned from the IPPN registry?Pediatric nephrology (Berlin, Germany) · 2021Review
- Nutritional Assessment and Management in Paediatric Chronic Kidney Disease.Journal of nutrition and metabolism · 2021Review
- Delivery of a nutritional prescription by enteral tube feeding in children with chronic kidney disease stages 2-5 and on dialysis-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.Pediatric nephrology (Berlin, Germany) · 2021Review
- Feeding patterns and outcomes of enterally tube fed paediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2020Article
- End-stage kidney disease in infancy: an educational review.Pediatric nephrology (Berlin, Germany) · 2020Review
- Strategies for Optimizing Growth in Children With Chronic Kidney Disease.Frontiers in pediatrics · 2020Review
- Catch-up growth in children with chronic kidney disease started on enteral feeding after 2 years of age.Pediatric nephrology (Berlin, Germany) · 2020Article
- Summary of Expert Opinion on the Management of Children With Chronic Kidney Disease and Growth Failure With Human Growth Hormone.Frontiers in endocrinology · 2020Article
- Nephrology and Public Policy Committee propositions to stimulate research collaboration in adults and children in Europe.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2019Article
Corrections and comments
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Authors and funding
21 authors at 19 institutions in 13 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Very young children with chronic kidney disease often have difficulty maintaining adequate nutrition, which contributes to the high prevalence of short stature in this population. Characteristics of the dialysis prescription and supplemental feeding via a nasogastric (NG) tube or gastrostomy may improve growth, but this is not well understood. Here, we analyzed data from 153 children in 18 countries who commenced chronic peritoneal dialysis at <24 months of age. From diagnosis to last observation, 57 patients were fed on demand, 54 by NG tube, and 10 by gastrostomy; 26 switched from NG to gastrostomy; and 6 returned from NG to demand feeding. North American and European centers accounted for nearly all feeding by gastrostomy. Standardized body mass index (BMI) uniformly decreased during periods of demand feeding and increased during NG and gastrostomy feeding. Changes in BMI demonstrated significant regional variation: 26% of North American children were obese and 50% of Turkish children were malnourished at last observation (P < 0.005). Body length decreased sharply during the first 6 to 12 months of life and then tended to stabilize. Time fed by gastrostomy significantly associated with higher lengths over time (P < 0.001), but adjustment for baseline length attenuated this effect. In addition, the use of biocompatible peritoneal dialysate and administration of growth hormone independently associated with improved length, even after adjusting for regional factors. In summary, growth and nutritional status vary regionally in very young children treated with chronic peritoneal dialysis. The use of gastrostomy feeding, biocompatible dialysis fluid, and growth hormone therapy associate with improved linear growth.
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