Evidence map›Paper›PMID 22021455›Full record

ArticleBlood2011

Is there still a place for myeloablative regimen to transplant young adults with sickle cell disease?

Mathieu Kuentz, Marie Robin, Nathalie Dhedin, Yosr Hicheri, Regis Peffault de Latour, Pierre Rohrlich, Pierre Bordigoni, Bénédicte Bruno, Gérard Socié, Françoise Bernaudin

Registry-linked trialAbstract readLetterComment
PubMed Publisher
In one paragraph

Article in Blood, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03240731 (Bone Marrow Transplantation HLA Haploidentical After a Reduced Intensity Conditioning and Prevention of GvHD Based on Post-transplant Cyclophosphamide Administration in Patients With Severe Sickle Cell Disease), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03240731 phase2completednot on this mapstarted 2017, after this paper: background citation

Bone Marrow Transplantation HLA Haploidentical After a Reduced Intensity Conditioning and Prevention of GvHD Based on Post-transplant Cyclophosphamide Administration in Patients With Severe Sickle Cell Disease

TypeinterventionalSponsorCentre Hospitalier Intercommunal CreteilRan2017 to 2024Enrolled25ConditionsSickle Cell DiseaseArmsbone marrow transplant
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Review
  5. Review
  6. Indications and Results of HLA-Identical Sibling Hematopoietic Cell Transplantation for Sickle Cell Disease.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2016
    Review
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mathieu Kuentz
Marie Robin
Nathalie Dhedin
Yosr Hicheri
Regis Peffault de Latour
Pierre Rohrlich
Pierre Bordigoni
Bénédicte Bruno
Gérard Socié
Françoise Bernaudin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellHematopoietic Stem Cell TransplantationHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.