ArticleThe Laryngoscope2011
In vivo oxygen consumption and hemoglobin levels in human thyroarytenoid muscle.
Article in The Laryngoscope, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 10 citations in OpenAlex.
- Exercise Science and the Vocalist.Journal of voice : official journal of the Voice Foundation · 2021Article
- Exercise Science and the Vocalist.Journal of voice : official journal of the Voice Foundation · 2021Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
objectives/hypothesisVisible light spectroscopy (VLS) is the technology behind the Food and Drug Administration-approved TSTAT device that is used to monitor tissue oxygen (StO(2)) and relative total hemoglobin (rtHb) levels by measuring reflected visible light. The purpose of this novel, pilot study was to determine if VLS is a reliable and valid method of measuring StO(2) and rtHb levels in the human thyroarytenoid/lateral cricoarytenoid (TA-LCA) muscle complex, thus providing information about vocal fold muscle physiology. STUDY
designPre-test/post-test with mulitple baselines and two conditions.
methodsVLS measurements were taken at baseline, during exercise, and following recovery on six subjects using both noncontact channel-port endoscope (endo-probe) and laryngeal electromyography (LEMG) needle-guided techniques.
resultsThe average baseline StO(2) was 69% (standard deviation [SD] = 3.6%) for the LEMG-guided probe and was 71.5% (SD = 2.8%) for the endo-probe. During phonation, the StO(2) for the LEMG-guided probe dropped to 59% (SD = 7%; P = .04). Mean rtHb measured by the LEMG probe rose from a baseline of 144 μM (SD = 165 μM) to 214 μM (SD = 166 μM, P = .34) during phonation and back to 149 μM (SD = 139 μM, P = .85) after recovery. Mean rtHb as measured using the endo-probe at baseline and after recovery was 104 μM (SD = 30 μM, P = .76).
conclusionsVLS can be used to measure changes in StO(2) and rtHb levels pre- and postexercise in the human TA-LCA muscle complex.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.