ArticleJournal of biomedical informatics2012
Development and evaluation of an ontology for guiding appropriate antibiotic prescribing.
Article in Journal of biomedical informatics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Using clinical reasoning ontologies to make smarter clinical decision support systems: a systematic review and data synthesis.Journal of the American Medical Informatics Association : JAMIA · 2020Pooled it
- Towards an ML-based semantic IoT for pandemic management: A survey of enabling technologies for COVID-19.Neurocomputing · 2023Article
- Ontologies Applied in Clinical Decision Support System Rules: Systematic Review.JMIR medical informatics · 2023Review
- OntoPharma: ontology based clinical decision support system to reduce medication prescribing errors.BMC medical informatics and decision making · 2022Article
- Developing an ontology for representing the domain knowledge specific to non-pharmacological treatment for agitation in dementia.Alzheimer's & dementia (New York, N. Y.) · 2020Article
- Issues Associated With the Use of Semantic Web Technology in Knowledge Acquisition for Clinical Decision Support Systems: Systematic Review of the Literature.JMIR medical informatics · 2017Article
- Reducing the Toxicity Risk in Antibiotic Prescriptions by Combining Ontologies with a Multiple Criteria Decision Model.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2017Article
- Combining expert knowledge and knowledge automatically acquired from electronic data sources for continued ontology evaluation and improvement.Journal of biomedical informatics · 2015Article
- Development of an informatics infrastructure for data exchange of biomolecular simulations: Architecture, data models and ontology.SAR and QSAR in environmental research · 2015Review
- Using description logics to evaluate the consistency of drug-class membership relations in NDF-RT.Journal of biomedical semantics · 2015Article
- Development of an obesity management ontology based on the nursing process for the mobile-device domain.Journal of medical Internet research · 2013Article
- Mobile monitoring and reasoning methods to prevent cardiovascular diseases.Sensors (Basel, Switzerland) · 2013Article
- Design and evaluation of a bacterial clinical infectious diseases ontology.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2013Article
- Ontological approach to reduce complexity in polypharmacy.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2013Article
- Transforming user needs into functional requirements for an antibiotic clinical decision support system: explicating content analysis for system design.Applied clinical informatics · 2013Article
- Deriving an abstraction network to support quality assurance in OCRe.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2012Article
- Ontological approach for safe and effective polypharmacy prescription.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectivesTo develop and apply formal ontology creation methods to the domain of antimicrobial prescribing and to formally evaluate the resulting ontology through intrinsic and extrinsic evaluation studies.
methodsWe extended existing ontology development methods to create the ontology and implemented the ontology using Protégé-OWL. Correctness of the ontology was assessed using a set of ontology design principles and domain expert review via the laddering technique. We created three artifacts to support the extrinsic evaluation (set of prescribing rules, alerts and an ontology-driven alert module, and a patient database) and evaluated the usefulness of the ontology for performing knowledge management tasks to maintain the ontology and for generating alerts to guide antibiotic prescribing.
resultsThe ontology includes 199 classes, 10 properties, and 1636 description logic restrictions. Twenty-three Semantic Web Rule Language rules were written to generate three prescribing alerts: (1) antibiotic-microorganism mismatch alert; (2) medication-allergy alert; and (3) non-recommended empiric antibiotic therapy alert. The evaluation studies confirmed the correctness of the ontology, usefulness of the ontology for representing and maintaining antimicrobial treatment knowledge rules, and usefulness of the ontology for generating alerts to provide feedback to clinicians during antibiotic prescribing.
conclusionsThis study contributes to the understanding of ontology development and evaluation methods and addresses one knowledge gap related to using ontologies as a clinical decision support system component-a need for formal ontology evaluation methods to measure their quality from the perspective of their intrinsic characteristics and their usefulness for specific tasks.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.