ArticleAtencion primaria2012
[Therapeutic non-compliance with insulin in the treatment of diabetes mellitus 2].
Article in Atencion primaria, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Efficacy and safety of oral insulin versus placebo for patients with diabetes mellitus: A systematic review and meta-analysis.Indian journal of pharmacologyPooled it
- Quasi-experimental controlled study protocol to reduce sedentary lifestyle in patients with type 2 diabetes.PloS one · 2025Article
- Non-adherence to non-insulin glucose-lowering drugs: Prevalence, predictors and impact on glycemic control and insulin initiation. A longitudinal cohort study in a large primary care database in Spain.The European journal of general practice · 2023Article
- Perspectives and Views of Primary Care Professionals Regarding DiabeText, a New mHealth Intervention to Support Adherence to Antidiabetic Medication in Spain: A Qualitative Study.International journal of environmental research and public health · 2022Article
- Patients' Views on the Design of DiabeText, a New mHealth Intervention to Improve Adherence to Oral Antidiabetes Medication in Spain: A Qualitative Study.International journal of environmental research and public health · 2022Article
- Patient Preferences for Pharmacological Diabetes Treatment Among People with Diabetes in Spain: A Discrete Choice Experiment.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2022Article
- Use of metformin and vildagliptin for treatment of type 2 diabetes in the elderly.Drug design, development and therapy · 2014Article
- [Adherence of Type 2 Diabetes Mellitus approach: Current situation and possible solutions].Atencion primaria · on this mapArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine the percentage of therapeutic noncompliance among type 2 diabetes patients on treatment with insulin.
designProspective multicentre study.
settingNine Primary Care Health Centre in Huelva (Spain).
participantsA total of 121 type 2 diabetics, who, in the opinion of their doctor, need to start treatment with insulin or have their insulin treatment modified. MAIN MEASUREMENTS: Five visits were made (enrolment, 6, 12, 18 and 24 months). The variables analysed were, fasting blood glucose, glycosylated haemoglobin, compliance with insulin treatment, measured by counting insulin units. The percentage compliance (PC) was calculated by (PC = Total No. of insulin units expected to be consumed / Total No. of insulin units that should have been taken x 100). A complier was considered as one who achieved a PC between 80 and 100%.
resultsThere were 103 evaluable subjects (85.8%) with a mean age of 66.4 (SD 11.6) years, and 45 were male (42.8%). The mean percentage compliance with insulin was 90.9% (95% CI, 84.2-97.6%). At the 6, 12, 18 and 24 months visits it was 92.1% (95% CI, 85.6-98.6%), 92.3, 90.1 and 89.2% (95% CI, 81.7-96.7%), respectively. Overall patient compliance was 74.75% (95% CI, 64.3-85.2%). For the visits, compliance was 82.5% (95% CI, 73.3-91.7%), 77.7%, 73.8% and 71.8% (95% CI, 60.9-82.7%), respectively (P<.05 initial-final).
conclusionsA quarter of the diabetic patients did not comply with their insulin treatment.
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