ArticleBioorganic & medicinal chemistry letters2011
Enzymatic synthesis of D-sorbose and D-psicose with aldolase RhaD: effect of acceptor configuration on enzyme stereoselectivity.
Article in Bioorganic & medicinal chemistry letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 43 citations in OpenAlex.
- Engineering of glycerol-derived aldolase pathway improves D-allulose synthesis in a glucose-glycerol dual-carbon system.Archives of microbiology · 2026Article
- Transforming monosaccharides: Recent advances in rare sugar production and future exploration.BBA advances · 2025Article
- Highly Efficient Synthesis of Rare Sugars from Glycerol in Endotoxin-FreeFoods (Basel, Switzerland) · 2023Article
- Research Advances of d-allulose: An Overview of Physiological Functions, Enzymatic Biotransformation Technologies, and Production Processes.Foods (Basel, Switzerland) · 2021Review
- Structure-based prediction and identification of 4-epimerization activity of phosphate sugars in class II aldolases.Scientific reports · 2017Article
- Efficient enzymatic synthesis of L-rhamnulose and L-fuculose.Bioorganic & medicinal chemistry letters · 2016Article
- Facile Enzymatic Synthesis of Ketoses.Angewandte Chemie (International ed. in English) · 2015Article
- Biosynthesis of l-Sorbose and l-Psicose Based on C-C Bond Formation Catalyzed by Aldolases in an Engineered Corynebacterium glutamicum Strain.Applied and environmental microbiology · 2015Article
- Biosynthesis of rare hexoses using microorganisms and related enzymes.Beilstein journal of organic chemistry · 2013Review
- One-pot four-enzyme synthesis of ketoses with fructose 1,6-bisphosphate aldolases from Staphylococcus carnosus and rabbit muscle.Carbohydrate research · 2012Article
- Construction of microbial platform for an energy-requiring bioprocess: practical 2'-deoxyribonucleoside production involving a C-C coupling reaction with high energy substrates.Microbial cell factories · 2012Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
It was previously reported that DHAP-dependent aldolase RhaD selectively chooses L-glyceraldehyde from racemic glyceraldehyde to produce l-fructose exclusively. Contrastingly, we discovered that D-glyceraldehyde is also tolerated as an acceptor and the stereoselectivity of the enzyme is lost in the corresponding aldol addition. Furthermore, we applied this property to efficiently synthesize two rare sugars D-sorbose and D-psicose.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.