Evidence map›Paper›PMID 22018066›Full record

ArticleJournal of the American Academy of Dermatology2011

Melanoma in adolescents and young adults (ages 15-39 years): United States, 1999-2006.

Hannah K Weir, Loraine D Marrett, Vilma Cokkinides, Jill Barnholtz-Sloan, Pragna Patel, Eric Tai, Ahmedin Jemal, Jun Li, Julian Kim, Donatus U Ekwueme

Abstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Skin Cancer in People of Color: A Systematic Review.American journal of clinical dermatology · 2022
    Pooled it
  3. Correlates of intentional tanning among adolescents in the United States: a systematic review of the literature.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2013
    Pooled it
  4. Effects of a Tailored Mobile Messaging Intervention for Indoor Tanning Cessation in Young Females: A Randomized Clinical Trial.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hannah K WeirDivision of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
Loraine D Marrett
Vilma Cokkinides
Jill Barnholtz-Sloan
Pragna Patel
Eric Tai
Ahmedin Jemal
Jun Li
Julian Kim
Donatus U Ekwueme

Funding

Molecular studies of T cell clones for adoptive therapyK23CA109115 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KIM, JULIAN A. · 2006 to 2010
$672k
NCI NIH HHS K23 CA109115
6 · The paper itself

Abstract

backgroundInvasive melanoma of the skin is the third most common cancer diagnosed among adolescents and young adults (aged 15-39 years) in the United States. Understanding the burden of melanoma in this age group is important to identifying areas for etiologic research and in developing effective prevention approaches aimed at reducing melanoma risk.

methodsMelanoma incidence data reported from 38 National Program of Cancer Registries and/or Surveillance Epidemiology and End Results statewide cancer registries covering nearly 67.2% of the US population were used to estimate age-adjusted incidence rates for persons 15-39 years of age. Incidence rate ratios were calculated to compare rates between demographic groups.

resultsMelanoma incidence was higher among females (age-adjusted incidence rates = 9.74; 95% confidence interval 9.62-9.86) compared with males (age-adjusted incidence rates = 5.77; 95% confidence interval 5.68-5.86), increased with age, and was higher in non-Hispanic white compared with Hispanic white and black, American Indians/Alaskan Natives, and Asian and Pacific Islanders populations. Melanoma incidence rates increased with year of diagnosis in females but not males. The majority of melanomas were diagnosed on the trunk in all racial and ethnic groups among males but only in non-Hispanic whites among females. Most melanomas were diagnosed at localized stage, and among those melanomas with known histology, the majority were superficial spreading. LIMITATIONS: Accuracy of melanoma cases reporting was limited because of some incompleteness (delayed reporting) or nonspecific reporting including large proportion of unspecified histology.

conclusionsDifferences in incidence rates by anatomic site, histology, and stage among adolescents and young adults by race, ethnicity, and sex suggest that both host characteristics and behaviors influence risk. These data suggest areas for etiologic research around gene-environment interactions and the need for targeted cancer control activities specific to adolescents and young adult populations.

Indexed as

AdolescentAdultAge FactorsEthnicityFemaleHumansIncidenceMaleMelanomaRegistriesRisk FactorsSEER ProgramSkin NeoplasmsUnited StatesYoung Adult

Identifiers

PMID22018066
PMCPMC3254089

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.