Evidence map›Paper›PMID 2201751›Full record

ArticleThe Journal of experimental medicine1990

Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues.

P Tekamp-Olson, C Gallegos, D Bauer, J McClain, B Sherry, M Fabre, S van Deventer, A Cerami

Abstract readComparative Study
In one paragraph

Article in The Journal of experimental medicine, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

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  12. Myeloperoxidase deficiency in mice exacerbates lung inflammation induced by nonviable Candida albicans.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2013
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  17. TRPM2 contributes to inflammatory and neuropathic pain through the aggravation of pronociceptive inflammatory responses in mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012
    Article
  18. Article
  19. Article
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

P Tekamp-OlsonChiron Corporation, Emeryville, California 94608.
C Gallegos
D Bauer
J McClain
B Sherry
M Fabre
S van Deventer
A Cerami

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cDNA clone of murine macrophage inflammatory protein 2 (MIP-2) has been isolated from a library prepared from lipopolysaccharide (LPS)-stimulated RAW 264.7 cells and the nucleotide sequence determined. This cDNA was used to clone cDNAs for human homologues of MIP-2 from a library prepared from phorbol myristate acetate-treated and LPS-stimulated U937 cells. Two homologues were isolated and sequenced. Human MIP-2 alpha and MIP-2 beta are highly homologous to each other and to a previously isolated gene, human gro/melanoma growth-stimulating activity (MGSA). These three human genes, MIP-2 alpha, MIP-2 beta, and gro/MGSA, constitute a sub-family within the cytokine family represented by platelet factor 4 and interleukin 8.

Indexed as

Amino Acid SequenceAnimalsBase SequenceCarrier ProteinsCell LineChemokine CXCL2Chemokines, CXCChemotactic FactorsCloning, MolecularDNAGene LibraryHumansIntercellular Signaling Peptides and ProteinsInterleukin-8MiceMolecular Sequence DataCarrier ProteinsChemokine CXCL2Chemokines, CXCChemotactic FactorsCXCL2 protein, humanCXCL3 protein, humanDNAIntercellular Signaling Peptides and ProteinsInterleukin-8Oligonucleotide Probes

Identifiers

PMID2201751
PMCPMC2188540

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.