ReviewInternational journal of environmental research and public health2011
Environmental isocyanate-induced asthma: morphologic and pathogenetic aspects of an increasing occupational disease.
Review in International journal of environmental research and public health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Stepping down the dose of inhaled corticosteroids for adults with asthma.The Cochrane database of systematic reviews · 2017Pooled it
- Review
- FOIM: Thermal Foaming of Shape Memory Polyurethane Foil.Macromolecular rapid communications · 2025Article
- Reduced Isocyanate Release Using a Waterproof, Resin-Based Cast Alternative Relative to Fiberglass Casts.Toxics · 2023Article
- Parental occupational exposure to solvents and autism spectrum disorder: An exploratory look at gene-environment interactions.Environmental research · 2023Article
- Polyurethane Adhesives Based on Oxyalkylated Kraft Lignin.Polymers · 2022Article
- Lignin as a Renewable Building Block for Sustainable Polyurethanes.Materials (Basel, Switzerland) · 2022Review
- Health effects of exposure to isocyanates in a car factory.Central European journal of public health · 2022Article
- Epigenetic Markers Are Associated With Differences in Isocyanate Biomarker Levels in Exposed Spray-Painters.Frontiers in genetics · 2021Article
- Blocking TRPA1 in Respiratory Disorders: Does It Hold a Promise?Pharmaceuticals (Basel, Switzerland) · 2016Review
- Residual Isocyanates in Medical Devices and Products: A Qualitative and Quantitative Assessment.Environmental health insights · 2016Article
- Genetic variants in TNFα, TGFB1, PTGS1 and PTGS2 genes are associated with diisocyanate-induced asthma.Journal of immunotoxicology · 2016Article
- A chemical mixer with dark-green nails.BMJ case reports · 2015Article
- Stress induced premature senescence: a new culprit in ovarian tumorigenesis?The Indian journal of medical research · 2014Review
- Inception cohort study of workers exposed to toluene diisocyanate at a polyurethane foam factory: initial one-year follow-up.American journal of industrial medicine · 2014Article
- Understanding factors that influence protective glove use among automotive spray painters.Journal of occupational and environmental hygiene · 2014Article
- Article
- IL-4 and IL-5 secretions predominate in the airways of wistar rats exposed to toluene diisocyanate vapor.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2014Article
- Prevention guidance for isocyanate-induced asthma using occupational surveillance data.Journal of occupational and environmental hygiene · 2013Article
- Imbalance of mitochondrial-nuclear cross talk in isocyanate mediated pulmonary endothelial cell dysfunction.Redox biology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Occupational diseases affect more and more people every year. According to the International Labour Organization (ILO), in 2000 an estimated amount of at least 160 million people became ill as a result of occupational-related hazards or injuries. Globally, occupational deaths, diseases and injuries account for an estimated loss of 4% of the Gross Domestic Product. Important substances that are related to occupational diseases are isocyanates and their products. These substances, which are used in a lot of different industrial processes, are not only toxic and irritant, but also allergenic. Although the exposure to higher concentrations could be monitored and restricted by technical means, very low concentrations are difficult to monitor and may, over time, lead to allergic reactions in some workers, ending in an occupational disease. In order to prevent the people from sickening, the mechanisms underlying the disease, by patho-physiological and genetical means, have to be known and understood so that high risk groups and early signs in the development of an allergic reaction could be detected before the exposure to isocyanates leads to an occupational disease. Therefore, this paper reviews the so far known facts concerning the patho-physiologic appearance and mechanisms of isocyanate-associated toxic reactions and possible genetic involvement that might trigger the allergic reactions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.