Evidence map›Paper›PMID 22016635›Full record

ReviewInternational journal of molecular sciences2011

Looking to the future: biomarkers in the management of pancreatic adenocarcinoma.

Jennifer L Spratlin, Karen E Mulder

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Relationship Between the Expression of OClinical drug investigation · 2017
    Article
  2. Article
  3. Article
  4. Article
  5. miR-143 inhibits the metastasis of pancreatic cancer and an associated signaling pathway.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer L SpratlinDepartment of Oncology, Cross Cancer Institute, School of Cancer, Imaging and Engineering Sciences, Faculty of Medicine and Dentistry, University of Alberta, 11560 University Avenue, Edmonton, Alberta, T6G 1Z2, Canada.
Karen E Mulder

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence and mortality of pancreas cancer converge. There has been little advancement in the treatment of pancreas cancer since the acceptance of gemcitabine as the standard therapy. Unfortunately, the efficacy of gemcitabine is dismal. While there is much discussion for the development of biomarkers to help direct therapy in this area, there is little action to move them into clinical practice. Herein, we review potential pancreatic cancer biomarkers and discuss the limitations in their implementation.

Indexed as

AdenocarcinomaAntimetabolites, AntineoplasticBiomarkers, TumorHumansOutcome Assessment, Health CarePancreatic NeoplasmsReproducibility of ResultsSensitivity and SpecificityAntimetabolites, AntineoplasticBiomarkers, TumorbiomarkercDKclinical trialsgemcitabinehCNT3hENT1oxaliplatinpancreatic adenocarcinomaSPARC

Identifiers

PMID22016635
PMCPMC3189759

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.