ArticleJournal of mathematical biology2012
Multiscale modelling of auxin transport in the plant-root elongation zone.
Article in Journal of mathematical biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- ZmPILS6 is an auxin efflux carrier required for maize root morphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Fluctuations in auxin levels depend upon synchronicity of cell divisions in a one-dimensional model of auxin transport.PLoS computational biology · 2023Article
- Multiscale Asymptotic Analysis Reveals How Cell Growth and Subcellular Compartments Affect Tissue-Scale Hormone Transport.Bulletin of mathematical biology · 2023Article
- Modeling reveals posttranscriptional regulation of GA metabolism enzymes in response to drought and cold.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- A field theory for plant tropisms.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Effective equations governing an active poroelastic medium.Proceedings. Mathematical, physical, and engineering sciences · 2017Article
- Morphological Plant Modeling: Unleashing Geometric and Topological Potential within the Plant Sciences.Frontiers in plant science · 2017Review
- Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Parsimonious Model of Vascular Patterning Links Transverse Hormone Fluxes to Lateral Root Initiation: Auxin Leads the Way, while Cytokinin Levels Out.PLoS computational biology · 2015Article
- GA(3) enhances root responsiveness to exogenous IAA by modulating auxin transport and signalling in Arabidopsis.Plant cell reports · 2015Article
- Systems analysis of auxin transport in the Arabidopsis root apex.The Plant cell · 2014Article
- Multiscale systems analysis of root growth and development: modeling beyond the network and cellular scales.The Plant cell · 2012Review
- Combined in silico/in vivo analysis of mechanisms providing for root apical meristem self-organization and maintenance.Annals of botany · 2012Article
- Mathematical analysis of long-distance polar auxin transport data of pin mutants questions the role of PIN1 as postulated in the chemi-osmotic theory.Physiologia plantarumArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In the root elongation zone of a plant, the hormone auxin moves in a polar manner due to active transport facilitated by spatially distributed influx and efflux carriers present on the cell membranes. To understand how the cell-scale active transport and passive diffusion combine to produce the effective tissue-scale flux, we apply asymptotic methods to a cell-based model of auxin transport to derive systematically a continuum description from the spatially discrete one. Using biologically relevant parameter values, we show how the carriers drive the dominant tissue-scale auxin flux and we predict how the overall auxin dynamics are affected by perturbations to these carriers, for example, in knockout mutants. The analysis shows how the dominant behaviour depends on the cells' lengths, and enables us to assess the relative importance of the diffusive auxin flux through the cell wall. Other distinguished limits are also identified and their potential roles discussed. As well as providing insight into auxin transport, the study illustrates the use of multiscale (cell to tissue) methods in deriving simplified models that retain the essential biology and provide understanding of the underlying dynamics.
Indexed as
Identifiers
22015980What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.