ReviewRespiratory physiology & neurobiology2012
Isolated in vitro brainstem-spinal cord preparations remain important tools in respiratory neurobiology.
Review in Respiratory physiology & neurobiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Endomorphin-2 (Endo2) and substance P (SubP) co-application attenuates SubP-induced excitation and alters frequency plasticity in neonatal rat in vitro preparations.Respiratory physiology & neurobiology · 2025Article
- The lesion site of organophosphorus-induced central apnea and the effects of antidotes.Scientific reports · 2023Article
- Maternal opioids age-dependently impair neonatal respiratory control networks.Frontiers in physiology · 2023Article
- Mu-opioid receptor-dependent transformation of respiratory motor pattern in neonatesFrontiers in physiology · 2022Article
- Gestational intermittent hypoxia increases susceptibility to neuroinflammation and alters respiratory motor control in neonatal rats.Respiratory physiology & neurobiology · 2018Review
- Current Perspectives for the use of Gonane Progesteronergic Drugs in the Treatment of Central Hypoventilation Syndromes.Current neuropharmacology · 2018Review
- Bimodal Respiratory-Locomotor Neurons in the Neonatal Rat Spinal Cord.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Postnatal development of eupneic ventilation and metabolism in rats chronically exposed to moderate hyperoxia.Respiratory physiology & neurobiology · 2014Article
- The vesicular glutamate transporter VGLUT3 contributes to protection against neonatal hypoxic stress.The Journal of physiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Isolated in vitro brainstem-spinal cord preparations are used extensively in respiratory neurobiology because the respiratory network in the pons and medulla is intact, monosynaptic descending inputs to spinal motoneurons can be activated, brainstem and spinal cord tissue can be bathed with different solutions, and the responses of cervical, thoracic, and lumbar spinal motoneurons to experimental perturbations can be compared. The caveats and limitations of in vitro brainstem-spinal cord preparations are well-documented. However, isolated brainstem-spinal cords are still valuable experimental preparations that can be used to study neuronal connectivity within the brainstem, development of motor networks with lethal genetic mutations, deleterious effects of pathological drugs and conditions, respiratory spinal motor plasticity, and interactions with other motor behaviors. Our goal is to show how isolated brainstem-spinal cord preparations still have a lot to offer scientifically and experimentally to address questions within and outside the field of respiratory neurobiology.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.