ArticleParasitology research2012
Development and evaluation of a dipstick assay in diagnosis of human fasciolosis.
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 17 citations in OpenAlex.
- Diagnosis of Human Trematode Infections.Advances in experimental medicine and biology · 2024Review
- Serological diagnosis of fasciolosis (Frontiers in veterinary science · 2023Review
- Membrane Technology for Rapid Point-of-Care Diagnostics for Parasitic Neglected Tropical Diseases.Clinical microbiology reviews · 2021Article
- Case Report: Fascioliasis Hepatica Precisely Diagnosed by Metagenomic Next-Generation Sequencing and Treated With Albendazole.Frontiers in medicine · 2021Article
- The global burden of fasciolosis in domestic animals with an outlook on the contribution of new approaches for diagnosis and control.Parasitology research · 2013Review
- Evaluation of the diagnostic efficacy of Fasciola adult worm vomit for serodiagnosis of human fasciolosis.Parasitology research · 2013Article
- Comparative characterization of microRNAs from the liver flukes Fasciola gigantica and F. hepatica.PloS one · 2012Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For the diagnosis of human fasciolosis, a new dipstick assay was developed and its diagnostic efficacy was evaluated in comparison to enzyme linked immunosorbent assay (ELISA) using Fasciola gigantica excretory-secretory antigen. Sera samples were collected from patients with confirmed fasciolosis and patients with other parasitic diseases as well as from normal healthy individuals. The sensitivity, specificity, and diagnostic accuracy of the dipstick assay as well as ELISA were 100%, 96.7%, and 98.3%, respectively. The dipstick assay is extremely easy to apply, rapid (15 min), with a visually interpreted result, field portable, inexpensive, reagent conservative, and as being both sensitive and specific in diagnosis of human fasciolosis; the test could be an acceptable alternative for use in clinical laboratories lacking specialized equipment needed for ELISA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.