Evidence map›Paper›PMID 22014821›Full record

ArticleThe Journal of urology2011

Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis.

Jonathan C Routh, Melanie Pennison, Ilina Rosoklija, Sarah Dobbins, Paul J Kokorowski, Katherine C Hubert, Lin Huang, Caleb P Nelson

Abstract readComparative Study
In one paragraph

Article in The Journal of urology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Does marginalization status and distance from the hospital impact the timing of pediatric pyeloplasty in a universal access-to-care system?Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan C RouthDepartment of Urology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA.
Melanie Pennison
Ilina Rosoklija
Sarah Dobbins
Paul J Kokorowski
Katherine C Hubert
Lin Huang
Caleb P Nelson

Funding

Training in Child Health Services Research and Implementation ScienceT32HS000063 · AHRQ · CHILDREN'S HOSPITAL BOSTON · PI GARABEDIAN, LAURA FADEN, WALSH, KATHLEEN ELIZABETH · 1994 to 2024
$7.6M
Research Training in Pediatric Urology/CHB T32T32DK060442 · NIDDK · CHILDREN'S HOSPITAL BOSTON · PI ADAM, ROSALYN M · 2002 to 2023
$2.5M
Clinical Outcomes for Siblings of Children with Vesico-Ureteral RefluxK23DK088943 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI NELSON, CALEB PENNELL · 2010 to 2014
$892k
Comparative Effectiveness of Vesicoureteral Reflux Treatments in ChildrenK08DK100534 · NIDDK · DUKE UNIVERSITY · PI ROUTH, JONATHAN C · 2014 to 2018
$671k
AHRQ HHS T32 HS000063AHRQ HHS T32-HS000063NIDDK NIH HHS K08 DK100534NIDDK NIH HHS K23 DK088943NIDDK NIH HHS K23-DK088943NIDDK NIH HHS T32 DK060442NIDDK NIH HHS T32-DK60442
6 · The paper itself

Abstract

purposeWe have previously shown that nonwhite patients with ureteropelvic junction obstruction undergo pyeloplasty at a younger age than white patients. The mechanisms behind this finding are unclear, since there is no known racial variation in the natural history of ureteropelvic junction obstruction. We used a detailed clinical database to explain this phenomenon. MATERIALS AND

methodsWe retrospectively reviewed all patients undergoing primary pyeloplasty at our institution between 1992 and 2008. More than 360 data points were abstracted for each patient, including self-reported race, socioeconomic status, symptom duration and presentation.

resultsOf 847 patients undergoing pyeloplasty during the study period 741 met inclusion criteria. Nonwhite patients underwent surgery at a younger age (0.6 years) than whites (2.6 years, p <0.0001). When stratified by timing of clinical presentation (prenatal vs postnatal), there was no significant difference in race among patients presenting prenatally (0.37 vs 0.36 years, p = 0.22). Nonwhite patients presenting postnatally were significantly younger than white patients (6.3 vs 8.2 years, p = 0.03). This finding appeared to be due to differences in age at initial clinical presentation (5.4 vs 7.0 years, p = 0.03) and in time from initial clinical presentation to urological evaluation (0.6 vs 3.2 months, p = 0.03). These differences persisted after correcting for other factors, including markers of socioeconomic status.

conclusionsConsistent with previous studies, we found that nonwhite patients underwent primary pyeloplasty at a younger age than whites. This difference is limited to patients presenting after birth. Prenatally diagnosed patients underwent surgery at similar ages regardless of race.

Indexed as

Healthcare DisparitiesAsianBlack or African AmericanChildChild, PreschoolFemaleHispanic or LatinoHumansInfantKidney PelvisMalePrenatal DiagnosisRetrospective StudiesTime FactorsUreteral ObstructionWhite People

Identifiers

PMID22014821
PMCPMC3826789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.