Evidence map›Paper›PMID 22014096›Full record

ReviewJournal of the International AIDS Society2011

Male circumcision for HIV prevention: current evidence and implementation in sub-Saharan Africa.

Richard G Wamai, Brian J Morris, Stefan A Bailis, David Sokal, Jeffrey D Klausner, Ross Appleton, Nelson Sewankambo, David A Cooper, John Bongaarts, Guy de Bruyn and 2 more

Abstract readReview
In one paragraph

Review in Journal of the International AIDS Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Men undergoing medical circumcision at a community health centre: Knowledge and attitudes.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Article
  3. Article
  4. Article
  5. HIV knowledge, attitudes and practices amongst patients with severe mental illnesses and chronic medical illnesses in Durban, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Recent Insights into the HIV/AIDS Pandemic.Microbial cell (Graz, Austria) · 2016
    Review
  14. Article
  15. A Review of HIV and Surgery in Africa.The open AIDS journal · 2016
    Article
  16. Strong Country Level Correlation between Syphilis and HSV-2 Prevalence.Journal of sexually transmitted diseases · 2016
    Article
  17. Article
  18. Article
  19. New prospects for a preventive HIV-1 vaccine.Journal of virus eradication · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Richard G WamaiDepartment of African-American Studies, Northeastern University, Boston, MA, USA. r.wamai@neu.edu
Brian J Morris
Stefan A Bailis
David Sokal
Jeffrey D Klausner
Ross Appleton
Nelson Sewankambo
David A Cooper
John Bongaarts
Guy de Bruyn
Alex D Wodak
Joya Banerjee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterosexual exposure accounts for most HIV transmission in sub-Saharan Africa, and this mode, as a proportion of new infections, is escalating globally. The scientific evidence accumulated over more than 20 years shows that among the strategies advocated during this period for HIV prevention, male circumcision is one of, if not, the most efficacious epidemiologically, as well as cost-wise. Despite this, and recommendation of the procedure by global policy makers, national implementation has been slow. Additionally, some are not convinced of the protective effect of male circumcision and there are also reports, unsupported by evidence, that non-sex-related drivers play a major role in HIV transmission in sub-Saharan Africa. Here, we provide a critical evaluation of the state of the current evidence for male circumcision in reducing HIV infection in light of established transmission drivers, provide an update on programmes now in place in this region, and explain why policies based on established scientific evidence should be prioritized. We conclude that the evidence supports the need to accelerate the implementation of medical male circumcision programmes for HIV prevention in generalized heterosexual epidemics, as well as in countering the growing heterosexual transmission in countries where HIV prevalence is presently low.

Indexed as

Circumcision, MaleAfrica South of the SaharaCommunicable Disease ControlHIV InfectionsHumansMale

Identifiers

PMID22014096
PMCPMC3207867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.