Evidence map›Paper›PMID 22012617›Full record

ArticleGenes & development2011

Stress puts TIA on TOP.

Pavel Ivanov, Nancy Kedersha, Paul Anderson

Abstract readComment
In one paragraph

Article in Genes & development, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Aging RNA granule dynamics in neurodegeneration.Frontiers in molecular biosciences · 2022
    Review
  5. Article
  6. Stress granule subtypes: an emerging link to neurodegeneration.Cellular and molecular life sciences : CMLS · 2020
    Review
  7. Stress Granules and Processing Bodies in Translational Control.Cold Spring Harbor perspectives in biology · 2019
    Review
  8. Translational Control under Stress: Reshaping the Translatome.BioEssays : news and reviews in molecular, cellular and developmental biology · 2019
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Stress granules, P-bodies and cancer.Biochimica et biophysica acta · 2015
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Pavel IvanovDivision of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
Nancy Kedersha
Paul Anderson

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Under conditions of limited nutrients, eukaryotic cells reprogram protein expression in a way that slows growth but enhances survival. Recent data implicate stress granules, discrete cytoplasmic foci into which untranslated mRNPs are assembled during stress, in this process. In the October 1, 2011, issue of Genes & Development, Damgaard and Lykke-Andersen (p. 2057-2068) provide mechanistic insights into the regulation of a specific subset of mRNAs bearing 5'-terminal oligopyrimidine tracts (5'TOPs) by the structurally related stress granule proteins TIA-1 and TIAR.

Indexed as

Gene Expression RegulationHumansPoly(A)-Binding ProteinsRNA 5' Terminal Oligopyrimidine SequenceRNA-Binding ProteinsRNA, MessengerPoly(A)-Binding ProteinsRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID22012617
PMCPMC3205582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.