ArticleClinics (Sao Paulo, Brazil)2011
Neuroendocrine tumors involving the gastroenteropancreatic tract: a clinicopathological evaluation of 773 cases.
Article in Clinics (Sao Paulo, Brazil), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed, 75 citations in OpenAlex.
- Analysis of clinicopathological characteristics and prognosis of appendiceal neuroendocrine tumors: a retrospective cohort study based on the SEER database.Translational cancer research · 2025Article
- Comparison of clinicopathological features and survival analysis between esophageal neuroendocrine carcinoma and esophageal squamous cell carcinoma based on the SEER database, alongside nomogram analysis for esophageal neuroendocrine carcinoma.Journal of gastrointestinal oncology · 2023Article
- Neuroendocrine tumour of the lesser omentum.BMJ case reports · 2023Article
- Clinical characteristics, prognostic factors, and survival trends in esophageal neuroendocrine carcinomas: A population-based study.Cancer medicine · 2022Article
- Article
- Clinicopathologic profile of gastroenteropancreatic neuroendocrine neoplasms in a referral center of South India.International journal of clinical and experimental pathology · 2022Article
- Neuroendocrine Tumors: Clinical, Histological and Immunohistochemical Perspectives and Case Report-Mature Teratoma in a 16-Year-Old Girl.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Article
- What is New in the 2019 World Health Organization (WHO) Classification of Tumors of the Digestive System: Review of Selected Updates on Neuroendocrine Neoplasms, Appendiceal Tumors, and Molecular Testing.Archives of pathology & laboratory medicine · 2021Review
- Histopathological landscape of rare oesophageal neoplasms.World journal of gastroenterology · 2020Review
- Histopathologist-level quantification of Ki-67 immunoexpression in gastroenteropancreatic neuroendocrine tumors using semiautomated method.Journal of medical imaging (Bellingham, Wash.) · 2020Article
- Colorectal neuroendocrine tumors: A case series.International journal of surgery case reports · 2020Article
- The clinicopathologic features and prognosis of esophageal neuroendocrine carcinomas: a single-center study of 53 resection cases.BMC cancer · 2019Article
- Composite Neuroendocrine and Squamous Cell Tumor of the Esophagus.ACG case reports journal · 2019Article
- Pediatric gastroenteropancreatic neuroendocrine tumor: A case report and review of the literature.Medicine · 2019Review
- A comparative analysis of clinicopathological factors between esophageal small cell and basaloid squamous cell carcinoma.Medicine · 2019Observational
- Primary hepatic neuroendocrine tumor case with a preoperative course of 26 years: A case report and literature review.World journal of gastroenterology · 2018Review
- Unusual Sites of High-Grade Neuroendocrine Carcinomas: A Case Series and Review of the Literature.The American journal of case reports · 2018Review
- Article
- Primary Esophagogastric Neuroendocrine Carcinoma: a Retrospective Study from the Nottingham Upper Gastrointestinal Cancer Center.Journal of gastrointestinal cancer · 2018Article
- Carcinoid tumour of the oesophagus: a systematic review.Przeglad gastroenterologiczny · 2018Review
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Authors and funding
2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveDescription of some of the clinical pathological characteristics of neuroendocrine tumors of the gastroenteropancreatic tract in Brazilian patients.
introductionNeuroendocrine tumors arise in many organs and share common pathological features. In 2010, the World Health Organization published a new classification for neuroendocrine tumors using a three-tiered system that applies the terms neuroendocrine tumor Grade 1, neuroendocrine tumor Grade 2, and neuroendocrine carcinoma. The tumor grades are based on their mitotic rate and the Ki-67 index. In Brazil, information on neuroendocrine tumors of gastroenteropancreatic tract is scarce.
methodsThis study investigated clinicopathological features of 773 Brazilian gastroenteropancreatic neuroendocrine tumor cases from all the geographic regions of Brazil. All of the cases emerged from the files of a single institution (a large pathology reference laboratory) between 1997 and 2009. In addition, the gastroenteropancreatic neuroendocrine tumors were graded according to the new 2010 World Health Organization classification.
resultsOverall there were a higher number of neuroendocrine tumors in female over male. The lower ages were seen in patients with appendiceal tumors. The most common anatomic location involved was stomach followed by small and large intestines. All cases involving the appendix were of grade 1 and 92.1% of the neuroendocrine tumors of the esophagus were neuroendocrine carcinomas (grade 3).
conclusionsIn this series, the proportion of NET cases in the total number of surgical pathology cases at our institution over the past 12 years is increasing.
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