Evidence map›Paper›PMID 22011570›Full record

ArticleArthritis research & therapy2011

Associations of educational attainment, occupation and community poverty with knee osteoarthritis in the Johnston County (North Carolina) osteoarthritis project.

Leigh F Callahan, Rebecca J Cleveland, Jack Shreffler, Todd A Schwartz, Britta Schoster, Randy Randolph, Jordan B Renner, Joanne M Jordan

Open access · goldAbstract readComparative Study
In one paragraph

Article in Arthritis research & therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.

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  12. Obesity and the Development of Arthritis Among Adults in the United States Using NHANES Data.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Leigh F CallahanThurston Arthritis Research Center, Department of Medicine, 3300 Thurston Building, CB # 7280, University of North Carolina, Chapel Hill, NC 27599-7330, USA. leigh_callahan@med.unc.edu
Rebecca J Cleveland
Jack Shreffler
Todd A Schwartz
Britta Schoster
Randy Randolph
Jordan B Renner
Joanne M Jordan
University of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
Women's knee motion patterns in functional activitiesP60AR030701 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CALLAHAN, LEIGH FLEMING · 1986 to 2001
$1.9M
Individual & Community Social Determinants of Osteoarthritis OutcomesR01AR053989 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CALLAHAN, LEIGH FLEMING · 2008 to 2012
$1.6M
NIAMS NIH HHS P60-AR30701NIAMS NIH HHS P60-AR49465NIAMS NIH HHS R01-AR-053-989-01NIEHS NIH HHS P30 ES010126PHS HHS S043PHS HHS S1733PHS HHS S3486
6 · The paper itself

Abstract

introductionThe purpose of this study was to examine data from the Johnston County Osteoarthritis (OA) Project for independent associations of educational attainment, occupation and community poverty with tibiofemoral knee OA.

methodsA cross-sectional analysis was conducted on 3,591 individuals (66% Caucasian and 34% African American). Educational attainment (< 12 years or ≥12 years), occupation (non-managerial or not), and census block group household poverty rate (< 12%, 12 to 25%, > 25%) were examined separately and together in logistic models adjusting for covariates of age, gender, race, body mass index (BMI), smoking, knee injury and occupational activity score. Outcomes were presence of radiographic knee OA (rOA), symptomatic knee OA (sxOA), bilateral rOA and bilateral sxOA.

resultsWhen all three socioeconomic status (SES) variables were analyzed simultaneously, low educational attainment was significantly associated with rOA (odds ratio (OR) = 1.44, 95% confidence interval (CI) 1.20, 1.73), bilateral rOA (OR = 1.43, 95% CI 1.13, 1.81), and sxOA (OR = 1.66, 95% CI 1.34, 2.06), after adjusting for covariates. Independently, living in a community of high household poverty rate was associated with rOA (OR = 1.83, 95% CI 1.43, 2.36), bilateral rOA (OR = 1.56, 95% CI 1.12, 2.16), and sxOA (OR = 1.36, 95% CI 1.00, 1.83). Occupation had no significant independent association beyond educational attainment and community poverty.

conclusionsBoth educational attainment and community SES were independently associated with knee OA after adjusting for primary risk factors for knee OA.

Indexed as

AgedCommunity Health ServicesCross-Sectional StudiesEducational StatusFemaleHumansMaleMiddle AgedModels, StatisticalNorth CarolinaOccupational DiseasesOsteoarthritisOsteoarthritis, KneePovertyRadiographyRisk Factors

Identifiers

PMID22011570
PMCPMC3308104
OpenAlexW2130755317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.