ArticlePlant physiology2011
Dominant and pleiotropic effects of a GAI gene in wheat results from a lack of interaction between DELLA and GID1.
Article in Plant physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 107 citations in OpenAlex.
- Editing a gibberellin receptor gene improves yield and nitrogen fixation in soybean.Journal of integrative plant biology · 2026Article
- Genetic mapping and isolation of Rht28, a locus on wheat chromosome arm 2AL affecting plant height, grain size, and grain weight.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Rht12b, a widely used ancient allele of TaGA2oxA13, reduces plant height and enhances yield potential in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Repression ofInternational journal of molecular sciences · 2023Article
- Fine mapping and characterization of a major QTL for plant height on chromosome 5A in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Analysis of morphological traits and regulatory mechanism of a semi-dwarf, albino, and blue grain wheat line.Molecular breeding : new strategies in plant improvement · 2023Article
- Fine mapping of reduced height locus RHT26 in common wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Fine mapping of the reduced height gene Rht22 in tetraploid wheat landrace Jianyangailanmai (Triticum turgidum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- The Association of Grain Yield and Agronomical Traits with Genes of Plant Height, Photoperiod Sensitivity and Plastid Glutamine Synthetase in Winter Bread Wheat (International journal of molecular sciences · 2022Article
- The fine mapping of dwarf gene Rht5 in bread wheat and its effects on plant height and main agronomic traits.Planta · 2022Article
- Fine mapping and candidate gene analysis of dwarf gene Rht14 in durum wheat (Triticum durum).Functional & integrative genomics · 2022Article
- A high-density linkage map of finger millet provides QTL for blast resistance and other agronomic traits.The plant genome · 2022Article
- Temperature response of wheat affects final height and the timing of stem elongation under field conditions.Journal of experimental botany · 2021Article
- Characterization of the GRAS gene family reveals their contribution to the high adaptability of wheat.PeerJ · 2021Article
- The Allelic Diversity of the Gibberellin Signaling Pathway Genes inPlants (Basel, Switzerland) · 2020Article
- Identification and validation of genetic loci for tiller angle in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Article
- TEOSINTE BRANCHED1 regulates height and stem internode length in bread wheat.Journal of experimental botany · 2020Article
- Genetic dissection of a major QTL for kernel weight spanning the Rht-B1 locus in bread wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Review
- Identification and characterization of a new dwarf locus DS-4 encoding an Aux/IAA7 protein in Brassica napus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
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Authors and funding
11 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dominance, semidominance, and recessiveness are important modes of Mendelian inheritance. The phytohormone gibberellin (GA) regulates many plant growth and developmental processes. The previously cloned semidominant GA-insensitive (GAI) genes Reduced height1 (Rht1) and Rht2 in wheat (Triticum aestivum) were the basis of the Green Revolution. However, no completely dominant GAI gene has been cloned. Here, we report the molecular characterization of Rht-B1c, a dominant GAI allele in wheat that confers more extreme characteristics than its incompletely dominant alleles. Rht-B1c is caused by a terminal repeat retrotransposons in miniature insertion in the DELLA domain. Yeast two-hybrid assays showed that Rht-B1c protein fails to interact with GA-INSENSITIVE DWARF1 (GID1), thereby blocking GA responses and resulting in extreme dwarfism and pleiotropic effects. By contrast, Rht-B1b protein only reduces interaction with GID1. Furthermore, we analyzed its functions using near-isogenic lines and examined its molecular mechanisms in transgenic rice. These results indicated that the affinity between GID1 and DELLA proteins is key to regulation of the stability of DELLA proteins, and differential interactions determine dominant and semidominant gene responses to GA.
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