ArticleThe Journal of biological chemistry2011
The composition of plant mitochondrial supercomplexes changes with oxygen availability.
Article in The Journal of biological chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 93 citations in OpenAlex.
- Mitochondrial respirasome-like supercomplexes support metabolic flexibility in yeast.Nature communications · 2026Article
- Review
- Comparative mitogenomics ofFrontiers in plant science · 2026Article
- Plant supercomplex I + III2 structure and function: implications for the growing field.Biochemical Society transactions · 2024Review
- OXPHOS Organization and Activity in Mitochondria of Plants with Different Life Strategies.International journal of molecular sciences · 2023Article
- The conditional mitochondrial protein complexome in the Arabidopsis thaliana root and shoot.Plant communications · 2023Article
- Try or Die: Dynamics of Plant Respiration and How to Survive Low Oxygen Conditions.Plants (Basel, Switzerland) · 2022Review
- Study of Tissue-Specific Reactive Oxygen Species Formation by Cell Membrane Microarrays for the Characterization of Bioactive Compounds.Membranes · 2021Article
- Article
- Sugar modulation of anaerobic-response networks in maize root tips.Plant physiology · 2021Article
- Metabolons, enzyme-enzyme assemblies that mediate substrate channeling, and their roles in plant metabolism.Plant communications · 2021Review
- The role of ethylene in metabolic acclimations to low oxygen.The New phytologist · 2021Review
- Mitochondrial respiratory chain composition and organization in response to changing oxygen levels.Journal of life sciences (Westlake Village, Calif.) · 2020Article
- Research journey of respirasome.Protein & cell · 2020Review
- Functional Mechanisms of Mitochondrial Respiratory Chain Supercomplex Assembly Factors and Their Involvement in Muscle Quality.International journal of molecular sciences · 2020Review
- Oncogenic pathways and the electron transport chain: a dangeROS liaison.British journal of cancer · 2020Review
- Expression of alternative NADH dehydrogenases (NDH-2) in the phytopathogenic fungusFEBS open bio · 2018Article
- Oxidative stress is tightly regulated by cytochromeProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Respiratory chain supercomplexes: Structures, function and biogenesis.Seminars in cell & developmental biology · 2018Review
- Oxygen Sensing and Integrative Stress Signaling in Plants.Plant physiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory supercomplexes are large protein structures formed by various enzyme complexes of the mitochondrial electron transport chain. Using native gel electrophoresis and activity staining, differential regulation of complex activity within the supercomplexes was investigated. During prolonged hypoxia, complex I activity within supercomplexes diminished, whereas the activity of the individual complex I-monomer increased. Concomitantly, an increased activity was observed during hypoxia for complex IV in the smaller supercomplexes that do not contain complex I. These changes in complex activity within supercomplexes reverted again during recovery from the hypoxic treatment. Acidification of the mitochondrial matrix induced similar changes in complex activity within the supercomplexes. It is suggested that the increased activity of the small supercomplex III(2)+IV can be explained by the dissociation of complex I from the large supercomplexes. This is discussed to be part of a mechanism regulating the involvement of the alternative NADH dehydrogenases, known to be activated by low pH, and complex I, which is inhibited by low pH. It is concluded that the activity of complexes within supercomplexes can be regulated depending on the oxygen status and the pH of the mitochondrial matrix.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.