ArticlePediatric blood & cancer2012
Excessive daytime sleepiness and sleep-disordered breathing disturbances in survivors of childhood central nervous system tumors.
Article in Pediatric blood & cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Sleep Disturbances in Pediatric Craniopharyngioma: A Systematic Review.Frontiers in neurology · 2022Pooled it
- Systematic Review: Sleep Disorders Based on Objective Data in Children and Adolescents Treated for a Brain Tumor.Frontiers in neuroscience · 2022Pooled it
- Investigating the Role of Hypothalamic Tumor Involvement in Sleep and Cognitive Outcomes Among Children Treated for Craniopharyngioma.Journal of pediatric psychology · 2016Trial
- Polysomnography analysis of sleep in a cohort of children treated for brain tumour.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Sleep disturbances in brain tumors: a narrative review.Frontiers in oncology · 2025Review
- Mechanisms of sleep disturbances in long-term cancer survivors: a childhood cancer survivor study report.JNCI cancer spectrum · 2024Article
- Secondary Narcolepsy as Worsening Sign in a Pediatric Case of Optic Pathway Glioma.Children (Basel, Switzerland) · 2022Article
- Article
- Prevalence of Sleep Disturbances in Pediatric Cancer Patients and Their Diagnosis and Management.Children (Basel, Switzerland) · 2021Review
- Sleep disturbances in craniopharyngioma: a challenging diagnosis.Journal of neurology · 2021Article
- Non-pharmacological sleep interventions for pediatric cancer patients and survivors: a systematic review protocol.Systematic reviews · 2021Article
- Sleep Disorders in Patients With Craniopharyngioma: A Physiopathological and Practical Update.Frontiers in neurology · 2021Review
- The importance of specialized sleep investigations in children with a suprasellar tumor.Pituitary · 2020Article
- Predictors of narcolepsy and hypersomnia due to medical disorder in pediatric craniopharyngioma.Journal of neuro-oncology · 2020Article
- A call to action for expanded sleep research in pediatric oncology: A position paper on behalf of the International Psycho-Oncology Society Pediatrics Special Interest Group.Psycho-oncology · 2020Review
- Sensitivity and Specificity of the Modified Epworth Sleepiness Scale in Children With Craniopharyngioma.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2019Article
- Sleep disorders in children with brain tumors: a pilot study based on a sleep disorder questionnaire.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Sleep and mood during hospitalization for high-dose chemotherapy and hematopoietic rescue in pediatric medulloblastoma.Psycho-oncology · 2018Article
- Prevalence, risk factors, and response to treatment for hypersomnia of central origin in survivors of childhood brain tumors.Journal of neuro-oncology · 2018Article
- Polysomnographic findings in craniopharyngioma patients.Sleep & breathing = Schlaf & Atmung · 2017Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundImprovements in treatment and management for pediatric central nervous system (CNS) tumors have increased survival rates, allowing clinicians to focus on long-term sequelae, including sleep disorders. The objective of this study was to describe a series of CNS tumor survivors who had sleep evaluations that included polysomnography (PSG) with attention to sleep disorder in relation to the tumor site. PROCEDURE: We report on 31 patients who had retrievable reports including an overnight PSG; 17 also underwent multiple sleep latency tests (MSLT) to characterize their sleepiness.
resultsMean age at tumor diagnosis was 7.4 years, mean age at sleep referral 14.3 years, and a mean time between tumor diagnosis and sleep referral of 6.9 years. The most common tumor location was the suprasellar region, the most common reason for sleep referral was excessive daytime sleepiness (EDS), and the most common sleep diagnosis was obstructive sleep apnea (n = 14) followed by central sleep apnea (n = 4), hypersomnia due to medical condition (n = 4), and narcolepsy (n = 3). Twenty-six of the 31 subjects were obese/overweight, and among those with the concurrent complaint of EDS, the mean sleep latency on MSLT was 3.16 minutes, consistent with excessive sleepiness.
conclusionsSuprasellar region tumor survivors who are obese or overweight are more likely to have complaints of EDS and are at greater risk of sleep-disordered breathing. Sleep-related symptoms may not be recognized and referral initiated until years after CNS diagnosis. A periodic and thorough sleep history should be taken when caring for CNS tumor survivors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.