Trial reportWorld journal of surgery2012
Diagnosing appendicitis at different time points in children with right lower quadrant pain: comparison between Pediatric Appendicitis Score and the Alvarado score.
Trial report in World journal of surgery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 41 citations in OpenAlex.
- Predicting Complicated Appendicitis: What Can Machine Learning Add?Diagnostics (Basel, Switzerland) · 2026Article
- Validation and Comparison of Pediatric Appendicitis Scores and Management Strategies (Project SPASMS): Protocol for a Prospective Multicenter Observational Study.JMIR research protocols · 2025Article
- A prospective study to evaluate the contribution of the pediatric appendicitis score in the decision process.BMC pediatrics · 2024Article
- Evaluation of a Previously Developed Predictive Model for Infective Endocarditis in 320 Patients Presenting with Fever at 4 Centers in Japan Between January 2018 and December 2020.Medical science monitor : international medical journal of experimental and clinical research · 2023Article
- Related Markers for the Precision Diagnosis of Complex Appendicitis in Children.Frontiers in pharmacology · 2022Review
- Increasing the Status of Hospital General Medicine Departments with Emphasis on Outpatient Care in Japan.International journal of general medicine · 2022Article
- Emergency Department Computed Tomography Use for Non-traumatic Abdominal Pain: Minimal Variability.The western journal of emergency medicine · 2018Article
- Multidetector computed tomography in the evaluation of pediatric acute abdominal pain in the emergency department.BioMedicine · 2016Article
- Pediatric gastric cancer presenting with massive ascites.World journal of gastroenterology · 2015Article
- An increase in CD3+CD4+CD25+ regulatory T cells after administration of umbilical cord-derived mesenchymal stem cells during sepsis.PloS one · 2014Article
- Etiology of non-traumatic acute abdomen in pediatric emergency departments.World journal of clinical cases · 2013Review
- Diagnosing appendicitis at different time points in children with right lower quadrant pain: comparison between pediatric appendicitis score and the Alvarado score.World journal of surgery · 2012Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute appendicitis is the most common abdominal emergency in clinical surgery. This study was designed to compare the diagnostic value of the Pediatric Appendicitis Score (PAS) with that of the Alvarado score based on different time points in children with right lower quadrant (RLQ) abdominal pain.
methodsThis prospective cohort study comprised 1,395 children (aged 3-18 years) with RLQ abdominal pain between 2005 and 2009. The patients were scored by the pediatric emergency physicians. Receiver operating characteristic (ROC) curves were used to determine the appropriate cutoff scores of the Alvarado and PAS systems. The sensitivity and specificity, and area under ROC curve were calculated for both systems.
resultsThe AUCs of the Alvarado system were all higher than those of the PAS system (day 1: 0.09 vs. 0.87; day 2: 0.87 vs. 0.84; day 3: 0.88 vs. 0.82). The best appropriate cutoff scores were seven (days 1 and 2) and six (day 3) on the PAS and six (days 1 and 2) and seven (day 3) on the Alvarado system.
conclusionsThe preliminary data show that the best cutoff score of Alvarado and PAS systems vary with the different time points of RLQ pain presentation. It may provide helpful information for primary or emergency physicians to determine whether the patient should undergo surgical consultation.
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